Abstract:<div>Abstract<p>Melanoma differentiation-associated gene-7/interleukin-24 (<i>mda</i>-7/IL-24) is a unique member of the <i>IL-10</i> gene family that induces cancer-selective growth suppression and apoptosis in a wide spectrum of human cancers in cell culture and animal models. Additionally, recent clinical trials confirm safety and document significant clinical activity of <i>mda</i>-7/IL-24 in patients with diverse solid cancers and melanomas. Despite intensiv… Show more
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