Abstract:<div>Abstract<p>Several components of the Wnt signaling cascade have been shown to function either as tumor suppressor proteins or as oncogenes in multiple human cancers, underscoring the relevance of this pathway in oncogenesis and the need for further investigation of Wnt signaling components as potential targets for cancer therapy. Here, using expression profiling analysis as well as <i>in vitro</i> and <i>in vivo</i> functional studies, we show that the Wnt pathway compo… Show more
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