Abstract:<div>Abstract<p>Lung cancer is the leading cause of cancer-associated mortality. Mutations in the <i>EGFR</i> gene are among the most important inducers of lung tumor development, but success of personalized therapies is still limited because of toxicity or developing resistances. We expressed constitutively active EGFR (EGFR<sup>CA</sup>) exclusively in the airway system of <i>Drosophila melanogaster</i> and performed comprehensive phenotyping. Ectopic expressio… Show more
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