Data-driven surrogate optimized and intensified extractive distillation process for clean separation of isopropanol from water: A sustainable alternative

Li, Xinyan; Wu, Jing; Yang, Lina; Wu, Xiaoqin; Man, Yi; Luo, Hao; Xiong, Qingang

doi:10.1016/j.jclepro.2022.135475

Cited by 8 publications

(1 citation statement)

References 39 publications

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“…Separation of high-purity isopropanol from aqueous solution is challenging due to an azeotrope (Table 1). Following recommendations from the literature, [39][40][41][42][43][44] extractive distillation with ethylene glycol was chosen for final isopropanol dehydration. Nonetheless, since the bottom product from column C2 contains only about 31.1 wt% of isopropanol, preconcentration is needed prior to dehydration by extractive distillation.…”

Section: Isopropanol Purificationmentioning

confidence: 99%

Advanced purification of isopropanol and acetone from syngas fermentation

Janković,

Straathof,

Kiss

2023

J of Chemical Tech & Biotech

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BACKGROUNDIsopropanol and acetone production by syngas fermentation is a promising alternative to conventional fossil carbon‐dependent production. However, this alternative technology has not yet been scaled up to an industrial level owing to the relatively low product concentrations (about 5 wt% in total). This original research aims to develop cost‐effective and energy‐efficient processes for the recovery of isopropanol and acetone from highly dilute fermentation broth (>94 wt% water) for large‐scale production (about 100 ktIPA+AC y−1).RESULTSVacuum distillation and pass‐through distillation enhanced with heat pumps or multi‐effect distillation were efficiently coupled with regular atmospheric distillation and extractive distillation in several innovative intensified downstream processes. Over 99.2% of isopropanol and 100% of acetone were recovered as high‐purity end‐products (>99.8 wt%). Advanced heat pumping (mechanical vapor recompression) and heat integration techniques were implemented to decrease total annual costs (0.109–0.137 USD kgIPA+AC−1), reduce energy requirements (1.348–2.043 kWth h kgIPA+AC−1) and lower CO2 emissions (0.067–0.191 kgCO2 kgIPA+AC−1), resulting in highly competitive recovery processes.CONCLUSIONThe proposed three novel isopropanol and acetone recovery processes from dilute broth significantly contribute to the expansion of sustainable industrial fermentation. Furthermore, this original research is the first one to develop novel pass‐through distillation technology for the complex isopropanol–acetone–water system. All the designed processes are highly economically competitive and environmentally viable. In addition to recovering efficiently both isopropanol and acetone, the designed downstream processes offer the possibility to enhance the fermentation process by recycling all the present microorganisms and reducing fresh‐water requirements. © 2023 The Authors. Journal of Chemical Technology and Biotechnology published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry (SCI).

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