Data-driven predictions of complex mixture permeation in polymer membranes

Abstract

Membrane-based organic solvent separations are rapidly emerging as a promising class of technologies for enhancing the energy efficiency of existing separation and purification systems. Polymeric membranes have shown promise in the fractionation or splitting of complex mixtures of organic molecules such as crude oil. Determining the separation performance of a polymer membrane when challenged with a complex mixture has thus far occurred in an ad hoc manner, and methods to predict the performance based on mixture composition and polymer chemistry are unavailable thus far. Here, we combine physics-informed machine learning algorithms and mass transport simulations to create an integrated predictive model for the separation of complex mixtures containing up to 400 components via any arbitrary linear polymer membrane. We experimentally demonstrate the effectiveness of the model by predicting the separation of two crude oils within 6-7 % of the measurements. Integration of ML predictors of key sorption and transport properties of molecules with transport simulators constitutes a radical departure from traditional approaches and will open new avenues for the rapid screening of polymer membranes prior to physical experimentation for the separation of complex liquid mixtures.

The physical basis for solvent flow in organic solvent nanofiltration

“…Polymeric membranes with very small pores may exhibit separation selectivity due to preferential size exclusion of one solvent component over the others, as the solvent mixture enters the membrane pores ( 3 ). However, in this case, solvent molecules within the pores still migrate collectively without discernible relative velocity differences ( 33 , 34 ), thus behaving like a unified flow.…”

Data-driven future for nanofiltration: Escaping linearity

“…ML models have already been demonstrated for NF ( Fetanat et al, 2021 ;Hu et al, 2021 ;Jeong et al, 2021 ;Hosseinzadeh et al, 2022 ;Ignacz et al, 2023 ;Lee et al, 2023 ;Zhu et al, 2023 ), RO ( Santos et al, 2007 ;Yangali-Quintanilla et al, 2009 ;Jeong et al, 2021 ;Zhu et al, 2023 ), and gas separation ( Barnett et al, 2020 ;Yang et al, 2022 ) applications ( Galinha and Crespo 2021 ). Currently, downstream predictive models usually output the desired parameters such as incompatibilities, material permeability, or any other material or process parameter.…”