“…Clearly, any state-discrete model belongs to this class, though it might be possible, that models with hybrid state-space are output-discrete if the continuous parts of the state-space are not considered as model-output. The best examples for this feature are found in classic microsimulation models or, to be precise, Markov models for health technology assessment (HTA, see [Abler et al, 2013]), wherein discrete health-states are observed, while (potentially) continuous patient parameters like age or blood values may have an influence on the transition probabilities between the health-states, but are not focus of interest. Anyway, in case of state-/output-discrete microscopic models there is a bijective mapping of Γ/Γ onto a subset of N d .…”