Das Seerecht

Stimulation of soluble ribonucleic acid methylase activity by polyamines

“…The effect of poly amines on the activity of sRNA methylases adds another item to a growing list of reactions influenced by these molecules. Polyamines have been reported to affect rRNA synthesis in sea urchins (Barros and Guidice, 1968), in vitro RNA polymerase activity (Abraham, 1968;Petersen et al, 1968), and binding of aminoacyl-tRNA to ribosomes (Tanner, 1967;Takeda, 1969). These observations, when correlated with the reported alterations in polyamine levels under varying growth conditions, make it increasingly plausible that polyamines participate in the regulation of macromolecular syntheses.…”