“…Several reasons may be advanced for this thrombotic tendency. Rytand (1937) suggested that it might be due to the decrease in circulating anti-thrombin which is one of the serum-albumins while Kollert and Starlinger (1926) demonstrated an increase in the fibrinogen content of the plasma in the nephrotic syndrome. The finding of abnormal lipoprotein ratios in cases of coronary thrombosis suggests that fat metabolism and the thrombotic state are closely related (Oliver and Boyd, 1953).…”