Das deutsche Forschungsnetz zu psychischen Erkrankungen

Abstract

Mental disorders are among the greatest medical and social challenges facing us. They can occur at all stages of life and are among the most important commonly occurring diseases. In Germany 28 % of the population suffer from a mental disorder every year, while the lifetime risk of suffering from a mental disorder is almost 50 %. Mental disorders cause great suffering for those affected and their social network. Quantitatively speaking, they can be considered to be among those diseases creating the greatest burden for society due to reduced productivity, absence from work and premature retirement. The Federal Ministry of Education and Research is funding a new research network from 2015 to 2019 with up to 35 million euros to investigate mental disorders in order to devise and develop better therapeutic measures and strategies for this population by means of basic and translational clinical research. This is the result of a competitive call for research proposals entitled research network for mental diseases. It is a nationwide network of nine consortia with up to ten psychiatric and clinical psychology partner institutions from largely university-based research facilities for adults and/or children and adolescents. Furthermore, three cross-consortia platform projects will seek to identify shared causes of diseases and new diagnostic modalities for anxiety disorders, attention deficit hyperactivity disorders (ADHS), autism, bipolar disorders, depression, schizophrenia and psychotic disorders as well as substance-related and addictive disorders. The spectrum of therapeutic approaches to be examined ranges from innovative pharmacological and psychotherapeutic treatment to novel brain stimulation procedures. In light of the enormous burden such diseases represent for society as a whole, a sustainable improvement in the financial support for those researching mental disorders seems essential. This network aims to become a nucleus for long overdue and sustained support for a German center for mental disorders.

Mapping Research Domain Criteria using a transdiagnostic mini-RDoC assessment in mental disorders: a confirmatory factor analysis

“…Overall, 1912 participants were recruited for the Phenotypic, Diagnostic and Clinical Domain Assessment Network Germany (PD-CAN) within the German research network for mental disorders [ 31 ]. All patients were initially recruited for specific intervention and observation studies of a given disease entity within each of the nine network consortia.…”

Biobanking in der Psychiatrie

“…Es kann mittlerweile als wissenschaftlicher Konsens gelten, dass bei wichtigen psychiatrischen Krankheitsbildern wie Demenzen, Psychosen und Depressionen ein erheblicher biologischer Pathogeneseanteil gegeben ist und dass die zukunftsfähige Erforschung psychischer Störungen die enge Verzahnung von klinischen und biologischen Ansätzen erfordert [5]. Die derzeit anhand der internationalen Klassifikationssysteme ICD-10 und DSM-V praktizierte klinische Diagnostik und Prognostik in der Psychiatrie basiert jedoch überwiegend auf der psychopathologischen Symptomerfassung ergänzt um subjektive Befindlichkeits-, Situations-und Verlaufsbeschreibungen seitens des Patienten und ggf.…”

“…Rechnung, indem transnosologisch komplexe Phänotypisierungen auf der Basis von Störungsmustern in normalpsychologischen Domänen angestrebt werden [5].…”

Traces of health—A landscape design task as a diagnostic aid for detecting mental burden? A qualitative focus group study

“…Epidemiological studies suggest that the prevalence of mental illness among adults in Germany is around 30% (Nübling et al, 2014), with around 1-2% being classified as severely mentally ill (Gühne et al, 2015). In order to recognize corresponding signs at an early stage in the sense of prevention, health promotion and prevention represent important cornerstones in patient-oriented healthcare systems (Bauer et al, 2016).…”