Darstellung von Alkylmethylphenylphosphanen nach der Methode von Hewertson und Watson / Preparation of Alkylmethylphenylphosphines by the Method of Hewertson and Watson

Abstract

<jats:p>The reaction of C<jats:sub>6</jats:sub>H<jats:sub>5</jats:sub>(CH<jats:sub>3</jats:sub>)PNa with some alkyl halides in liquid ammonia was studied. The resulting phosphines were characterized by elemental analyses, NMR spectra, and by the reaction with trimethylsilyl azide giving trimethylsilylimino triorganophosphoranes.</jats:p>

A Simple Resolution Procedure Using the Staudinger Reaction for the Preparation of P-Stereogenic Phosphine Oxides

“…Phosphines containing two alkyl substituents, one of which was methyl, and an aryl group were prepared via LiAlH 4 reduction of a suitably substituted phosphonium salt 6 (Scheme 2) that was generated from phosphine 5 . In this manner, racemic phosphines 7 − 9 were prepared and exhibited physical and spectral properties consistent with the literature …”

Intramolecular Nucleophilic Substitution of ω-Haloalkylphosphine Derivatives

“…The other methods have limited applications and include the radical addition of P­(O)­H-type compounds to cycloalkenes, the nucleophilic substitution with phosphorus nucleophiles, and the cyclization reactions . In classic organic chemistry, the formation of the cyclic framework could also be achieved by a reaction of the stabilized carbanions, predominantly derived from electron-withdrawing group–CH 2 –electron-withdrawing group (EWG–CH 2 –EWG) systems, with α,ω-dihaloalkanes, but in organophosphorus chemistry, this approach is barely developed.…”