DARS expression in BCR/ABL1-negative myeloproliferative neoplasms and its association with the immune microenvironment
Hao Xiong,
Minjing Liao,
Huitao Zhang
et al.
Abstract:DARS
, encoding for aspartyl-tRNA synthetase, is implicated in the pathogenesis of various cancers, including renal cell carcinoma, glioblastoma, colon cancer, and gastric cancer. Its role in
BCR/ABL1
-negative myeloproliferative neoplasms (MPNs), however, remains unexplored. This study aimed to elucidate the expression of
DARS
in patients with MPNs (PV 23, ET 19, PMF 16) through immunohistochemical analysis and to examine the profiles of circulating imm… Show more
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