Dark matter particles could annihilate into light and metastable mediators subsequently decaying far away from where they are produced. In this scenario, the indirect signatures of dark matter are altered with respect to the conventional situation where standard model particles are directly injected where annihilation happens. We revisit the long-lived particle proposal (Rothstein et al., 2009) and devise the tools to explore this new phenomenology.We calculate the effective dark matter distribution resulting from the smearing by mediator propagation. We derive general expressions for the fluxes of mediators and their decay particles. We study how the J-factor, which naturally appears in the calculation of the dark matter induced gamma ray signal, is modified in the presence of mediators. We also derive the anisotropy which the cosmic ray positron flux exhibits in this scenario. We finally comment upon a recent proposal based on long-lived mediators where the effective dark matter density at the Earth is increased such as to explain the cosmic ray positron anomaly.We conclude that this scenario is barely tenable as regards the very dense dark matter spike which it requires at the Galactic center. The associated positron anisotropy is very small and undetectable, except at high energies where it reaches a level of order 10 −4 to 10 −based on non-relativistic long-lived mediators, observations of the gamma ray emission from the GC no longer preclude the large values of the WIMP annihilation cross section required to explain the cosmic ray positron excess. The other difference lies in the small mass and high energy of the mediators. In general, these particles are relativistic at the time of annihilation and lead to anisotropic distributions of cosmic rays. In this paper, we set up the formalism for computing the fluxes and associated anisotropies of the prompt species -positrons and photons -produced in the decays of these long-lived mediators.The paper is organized as follows. In section II A, we show how the DM density profile is smeared by mediators and compute the production rate of SM particles yielded by mediator decay.The conventional situation is recovered if the DM density is replaced by an effective value which depends on the mediator properties. In the scenario proposed by [14] to explain the cosmic ray positron excess, the effective DM density at the Earth is exceedingly large with respect to its actual value. The price to pay for such an enhancement is the existence of a very dense DM spike at the GC. In section II B we ponder upon possible astrophysical mechanisms which can alter the Galactic density profiles and show that adiabatic contraction resulting from the formation of the GC black hole can marginally lead to the desired DM density. In section III, we build the formalism for computing the fluxes of mediators and prompt decay particles. The observable flux of gamma rays is then described by an effective J-factor, which, for very long-lived mediators, considerably differs from the canonical one. ...