We present the concentration (c)Yvirial mass (M ) relation of 39 galaxy systems ranging in mass from individual early-type galaxies up to the most massive galaxy clusters, (0:06Y20) ; 10 14 M . We selected for analysis the most relaxed systems possessing the highest quality data currently available in the Chandra and XMM-Newton public data archives. A power-law model fitted to the X-ray c-M relation requires at high significance (6.6 ) that c decreases with increasing M, which is a general feature of CDM models. The median and scatter of the c-M relation produced by the flat, concordance ÃCDM model ( m ¼ 0:3, 8 ¼ 0:9) agrees with the X-ray data, provided that the sample is comprised of the most relaxed, early-forming systems, which is consistent with our selection criteria. When allowing only 8 to vary in the concordance model, the c-M relation requires 0:76 < 8 < 1:07 (99% confidence), assuming a 10% upward bias in the concentrations for early-forming systems. The tilted, low-8 model suggested by a new WMAP analysis is rejected at 99.99% confidence, but a model with the same tilt and normalization can be reconciled with the X-ray data by increasing the dark energy equation of state parameter to w % À0:8. When imposing the additional constraint of the tight relation between 8 and m from studies of cluster abundances, the X-ray c-M relation excludes (>99% confidence) both open CDM models and flat CDM models with m % 1. This result provides novel evidence for a flat, low-m universe with dark energy using observations only in the local (zT1) universe. Possible systematic errors in the X-ray mass measurements of a magnitude %10% suggested by CDM simulations do not change our conclusions.