Daphne l. Türlerinin kimyasal içeriği ve biyolojik aktiviteleri : chemical constituents and biological activities of daphne l. Species

Tosun, Alev

doi:10.1501/eczfak_0000000045

Cited by 3 publications

(2 citation statements)

References 33 publications

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“…The origin of YN is uncertain. It was probably first isolated from the aerial parts of Daphne genkwa in China [ 92 , 93 , 94 ] and then from D. sericea [ 95 ]. The compound has been found also in the aerial parts of D. papyracea [ 96 ] and D. pedunculata H.F.Zhou ex C.Y.Chang [ 97 , 98 ].…”

Section: The Flavonoid Yuanhuanin (Yn)mentioning

confidence: 99%

Yuanhuacin and Related Anti-Inflammatory and Anticancer Daphnane Diterpenes from Genkwa Flos—An Overview

Bailly

2022

Biomolecules

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The dried flower buds of the plant Daphne genkwa Sieb. et Zucc. have been largely used in traditional Chinese medicine for the treatment of inflammatory diseases. Numerous diterpenoids have been isolated from the Genkwa Flos (yuanhua in Chinese), including a series of daphnane-type diterpene designated as yuanhuacin (YC, often improperly designated as yuanhuacine) and analogues with a patronymic name. The series includes ten daphnane-type diterpenes: yuanhuacin, yuanhuadin (YD), yuanhuafin (YF), yuanhuagin (YG), yuanhuahin (YH), yuanhuajin (YJ), yuanhualin (YL), yuanhuamin (YM), yuanhuapin (YP), and yuanhuatin (YT). They are distinct from the rare flavonoid yuanhuanin. The series comprises several anticancer agents, such as the lead compound YC, which has revealed potent activity in vitro and in vivo against models of lung and breast cancers. The main signaling pathways implicated in the antitumor effects have been delineated. Protein kinase C is a key factor of activity for YC, but in general the molecular targets at the origin of the activity of these compounds remain little defined. Promising anticancer effects have been reported with analogues YD and YT, whereas compounds YF and YP are considered more toxic. The pharmacological activity of each compound is presented, as well as the properties of Genkwa Flos extracts. The potential toxic effects associated with the use of these compounds are also underlined.

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Section: The Flavonoid Yuanhuanin (Yn)mentioning

confidence: 99%

Yuanhuacin and Related Anti-Inflammatory and Anticancer Daphnane Diterpenes from Genkwa Flos—An Overview

Bailly

2022

Biomolecules

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“…2020; Elfaki Ibrahim and Al-Khalifa 2021). Therefore, more comprehensive and detailed studies are needed regarding the high-dose and longer-exposure applications of M. chamomilla aqueous leaf extract against T. urticae.It has been reported that the chemical content of D. odora consists of avonoids, coumarins, terpenoids, steroids, and lignan compounds(Tosun 2006). There is limited scienti c research examining the acaricidal activity of…”

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confidence: 99%

Acaricidal efficacy of aqueous extracts from different plants on Tetranychus urticae Koch, 1836 (Acari: Tetranychidae)

Alpkent,

Ulusoy,

ERTÜRK

2023

Preprint

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The two-spotted spider mite (Tetranychus urticae Koch,1836, Acari: Tetranychidae) causes significant yield losses in cultivated plants, especially depending on the season. Chemical methods are the main methods of controlling this pest. However, besides the environmental, human, and animal health problems arising from chemical control, adverse effects such as resistance and residues limit the success and sustainability of chemical control. In this study, the potential acaricidal effect of aqueous extracts of Morus rubra, Daphne odora, Ficus carica, Matricaria chamomilla, and Mentha pulegium collected from Ankara and Adana provinces on T. urticae was investigated. For this purpose, the leaves of the plants were dried and ground and 1%, 3%, 6%, and 12% concentrations (v/v) of the extracts obtained were tested in three different application periods (1-6-day). Dipping and spraying methods were used to determine mortality and toxicity. The highest effect was 94.4% at the end of the 6th day at a 12% concentration of M. pulegium in the dipping method. On the other hand, the lowest mortality effect was 18.2% at the same time and concentration of M. chamomilla. In lethal toxicity studies, the highest toxicity was obtained from F. carica with an LC50 value of 4756 mg L− 1, and the lowest toxicity was obtained from D. odora with an LC50 value of 12417 mg L− 1. We believe that plant extracts provide a valid alternative in effectively controlling two-spotted spider mites, reducing the need for pesticide use and minimizing residues.

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Acaricidal efficacy of aqueous extracts from different plants on Tetranychus urticae Koch, 1836 (Acari: Tetranychidae)

Alpkent,

Ulusoy,

Ertürk

2024

J Plant Dis Prot

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Daphne l. Türlerinin kimyasal içeriği ve biyolojik aktiviteleri : chemical constituents and biological activities of daphne l. Species

Abstract: ABSTRACT

Cited by 3 publications

References 33 publications

Yuanhuacin and Related Anti-Inflammatory and Anticancer Daphnane Diterpenes from Genkwa Flos—An Overview

Yuanhuacin and Related Anti-Inflammatory and Anticancer Daphnane Diterpenes from Genkwa Flos—An Overview

Acaricidal efficacy of aqueous extracts from different plants on Tetranychus urticae Koch, 1836 (Acari: Tetranychidae)

Acaricidal efficacy of aqueous extracts from different plants on Tetranychus urticae Koch, 1836 (Acari: Tetranychidae)

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