Dapagliflozin-Induced Vulvovaginitis in an Atopic Patient with Type 2 Diabetes Mellitus

Vulvar Pruritus in Postmenopausal Diabetic Women With Candidiasis Secondary to Sodium-Glucose Cotransporter Receptor-2 Inhibitors

“…By reducing proximal tubular glucose reabsorption, they lower blood glucose levels without reliance on endogenous insulin release. Renal excretion of glucose has metabolic and cardiovascular benefits, including weight loss and blood pressure reduction, with a low hypoglycemia risk 1–4 . This pharmacologically induced glucosuria provides optimal conditions for microorganismal overgrowth within the urogenital tract, predisposing patients to genital mycotic infections (GMIs).…”

“…Renal excretion of glucose has metabolic and cardiovascular benefits, including weight loss and blood pressure reduction, with a low hypoglycemia risk. [1][2][3][4] This pharmacologically induced glucosuria provides optimal conditions for microorganismal overgrowth within the urogenital tract, predisposing patients to genital mycotic infections (GMIs). Although a well-described adverse effect, GMIs may be missed when presenting atypically in postmenopausal women.…”