Dandy-Walker Variant : Prenatal Diagnosis by Ultrasonography

Twenty years of misdiagnosis of schizophrenia in a patient with Dandy-Walker variant syndrome

“…Usually, these patients are girls, very young at their first psychotic episode, presenting different combinations of psychotic symptoms and cognitive impairment, and may have up to 10 years before the correct diagnosis is arrived at through a simple brain scan (table 1). One could say that there are studies describing brain volume changes in humans taking chronic antipsychotic medication,15 but we believe that was not the case with our patient, as Dandy-Walker variant syndrome has been widely recognised as a congenital neurodevelopment condition,16 not an iatrogenic neurodegenerative one. On the other hand, there are also studies pointing to cerebellar dysfunction in schizophrenia,17 but again, our patient’s psychosis probably never met the full clinical criteria for a schizophrenia diagnosis.…”

Moebius syndrome with Dandy-Walker variant and agenesis of corpus callosum

“…[ 6 ] Dandy-Walker variant includes vermian hypoplasia and cystic dilation of the 4 th ventricle without enlargement of the posterior fossa. [ 7 ] The child we report also has clinical features suggestive of Moebius syndrome with MRI findings consistent with complete agenesis of corpus callosum with Dandy-Walker variant.…”

Dandy –Walker Malformation with Patent Ductus Arteriosus– A Case Report

“…However, the third variant megacisterna magna comprises enlarged cistern magna with normal cerebellar vermis and fourth ventricle. 14 The Dandy -Walker Malformation is frequently associated with other central nervous system abnormalities including dysgenesis of corpus callosum like our case, ectopic brain tissue, holoprosencephaly, and neural tube defects. 15 Other associated extra cranial birth defects in DWM includes cardiac defects-patent ductus arteriosus (PDA) like our case; atrial septal defects(ASD), tetralogy of fallot (TOP), and eye or thyroid dysfunctions.…”