Damage to and recovery of coastlines polluted with C-heavy oil spilled from the Nakhodka

Hayakawa, Kazuichi; Nomura, Maki; Nakagawa, Takuya; Oguri, Seiji; Kawanishi, Takuya; Toriba, Akira; Kizu, Ryoichi; Sakaguchi, Toshifumi; Tamiya, Eiichi

doi:10.1016/j.watres.2005.12.035

Cited by 33 publications

(23 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the Cheavy oil of the Nakhodka, 210 g/g of BaA having four aromatic rings was detected [5]. This concentration is similar to that in the present experiment.…”

Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

“…Furthermore, an oil spill from an oil tanker, such as the Exxon Valdez and Nakhodka, directly induces contamination by PAHs in a marine environment [3][4][5]. In the Nakhodka Cheavy oil, 210 g/g of benz [a]anthracene having four aromatic rings was detected [5]. In developing teleosts, it has been reported that spinal deformity was induced in Pacific herring and pink salmon by PAHs [6,7] although the detail mechanism of toxicity in teleosts has not elucidated yet.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Toxic effect of polycyclic aromatic hydrocarbon metabolites on fish bone metabolism

Hayakawa

Suzuki

Kitamura

et al. 2010

WIT Transactions on Ecology and the Environment

View full text Add to dashboard Cite

Marine water is contaminated with polycyclic aromatic hydrocarbons (PAHs) from rivers and the atmosphere. Oil spilled from tankers or petroleum factories also causes marine pollution with PAHs. It is well known that PAHs, such as benzo [a]pyrene, show carcinogenicity and/or mutagenicity. In developing teleost fish, furthermore, it has been reported that spinal deformity was induced in Pacific herring and pink salmon by PAHs, although the detail mechanism of toxicity in teleosts is not elucidated yet. As a toxic pathway of PAHs in animals, the metabolic activation of PAHs in the presence of P450 is considered. In teleosts, as well as in mammals, it has been reported that PAHs are converted into monohydroxylated polycyclic aromatic hydrocarbons (OHPAHs) by an enzyme: cytochrome P4501A1. Thus, OHPAH might have a toxic effect in teleosts. In the present study, we examined the estrogenic activity of OHPAHs using the yeast-two hybrid assay system with human estrogen receptor ER) . As a result, we detected estrogenic activity in 4-hydroxybenz[a]anthracene (4-OHBaA). Then, the direct effect of 4-OHBaA on osteoclasts and osteoblasts in teleosts was examined using the assay system with fish scales, which contain osteoclasts, osteoblasts, and the bone matrix of two layers (bony layer: a thin, well-calcified external layer; a fibrillary layer: a thick, partially calcified layer). When the scales of goldfish and wrasse were incubated with 4-OHBaA, which showed agonistic activity in the yeast-two hybrid assay system described above, the suppressing effect was observed for both osteoclasts and osteoblasts. The osteoclastic and osteoblastic activities did not change with 1-hydroxypyrene, which has no binding activity to human ER. Thus, we conclude that PAH metabolites have a toxic effect on fish bone metabolism and that careful attention should be given to aquatic PAH contamination.

show abstract

“…In the Cheavy oil of the Nakhodka, 210 g/g of BaA having four aromatic rings was detected [5]. This concentration is similar to that in the present experiment.…”

Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Toxic effect of polycyclic aromatic hydrocarbon metabolites on fish bone metabolism

Hayakawa

Suzuki

Kitamura

et al. 2010

WIT Transactions on Ecology and the Environment

View full text Add to dashboard Cite

show abstract

“…In addition, accidental oil spills have occurred. Big oil spills from the Deepwater Horizon and sunken oil tanker ships (the Exxon Valdez and the Nakhodka) directly caused oil pollution in the marine environment and affected marine organisms (Bue et al, 1998;Heintz et al, 2000;Hayakawa et al, 2006;de Soysa et al, 2012). Oil contamination can seriously impact the marine environment toxicologically.…”

Section: Introductionmentioning

confidence: 99%

“…Oil contamination can seriously impact the marine environment toxicologically. Polycyclic aromatic hydrocarbons (PAHs) are toxic substances in oil (Hayakawa et al, 2006). For a long time (more than 14 years) after big oil spill from the Exxon Valdez, the toxicity of PAHs originating from spilled oil has been observed in numerous marine animals (Peterson, 2003).…”

Section: Introductionmentioning

confidence: 99%

Seawater Polluted with Highly Concentrated Polycyclic Aromatic Hydrocarbons Suppresses Osteoblastic Activity in the Scales of Goldfish,Carassius auratus

Suzuki¹,

Sato²,

Nassar³

et al. 2016

Zoological Science

Self Cite

View full text Add to dashboard Cite

We have developed an original in vitro bioassay using teleost scale that has osteoclasts, osteoblasts, and bone matrix as each marker: alkaline phosphatase (ALP) for osteoblasts and tartrate-resistant acid phosphatase (TRAP) for osteoclasts. Using this scale in vitro bioassay, we examined the effects of seawater polluted with highly concentrated polycyclic aromatic hydrocarbons (PAHs) and nitro-polycyclic aromatic hydrocarbons (NPAHs) on osteoblastic and osteoclastic activities in the present study. Polluted seawater was collected from 2 sites (the Alexandria site on the Mediterranean Sea and the Suez Canal site on the Red Sea). Total levels of PAHs in the seawater from the Alexandria and Suez Canal sites were 1364.59 and 992.56 ng/l, respectively. We can detect NPAHs in both seawater samples. Total levels of NPAHs were detected in the seawater of the Alexandria site (12.749 ng/l) and the Suez Canal site (3.914 ng/l). Each sample of polluted seawater was added into culture medium at dilution rates of 50, 100, and 500 and incubated with the goldfish scales for 6 hrs. Thereafter, ALP and TRAP activities were measured. As a result, ALP activity was significantly suppressed by both polluted seawater samples diluted at least 500 times, although TRAP activity did not change. In addition, mRNA expressions of osteoblastic markers (ALP, osteocalcin, and the receptor activator of the NF-B ligand) decreased significantly, as did the ALP enzyme activity. Actually, ALP activity decreased with selected PAHs and NPAHs treatments. We conclude that seawater polluted with highly concentrated PAHs and NPAHs influenced bone metabolism in teleosts.

show abstract

Toxicities of Polycyclic Aromatic Hydrocarbons in Fish and Marine Invertebrates

Suzuki

Ikari

Sato

et al. 2018

Polycyclic Aromatic Hydrocarbons

View full text Add to dashboard Cite

Damage to and recovery of coastlines polluted with C-heavy oil spilled from the Nakhodka

Cited by 33 publications

References 13 publications

Toxic effect of polycyclic aromatic hydrocarbon metabolites on fish bone metabolism

Toxic effect of polycyclic aromatic hydrocarbon metabolites on fish bone metabolism

Seawater Polluted with Highly Concentrated Polycyclic Aromatic Hydrocarbons Suppresses Osteoblastic Activity in the Scales of Goldfish,Carassius auratus

Toxicities of Polycyclic Aromatic Hydrocarbons in Fish and Marine Invertebrates

Contact Info

Product

Resources

About