“…Current indications for TIVS include: replantation, open extremity fractures with concurrent extensive soft tissue loss and arterial injury (Gustilo IIIC), peripheral vascular damage control, truncal vascular damage control, and temporary stabilization prior to transport [37,43]. Although the understanding of TIVS use for military and civilian settings is increasing [42], the optimal shunt material, dwell time, and anticoagulation requirements remain poorly studied; it is clear, however, that TIVS are remarkably durable and rarely clot unless they are too small (diameter), kink because of inappropriate length, and/or are placed in an extremity without appropriate (or shunted) venous outflow (venous hypertension leads to arterial thrombosis) [43].…”