Abstract:Persistent intra-abdominal sepsis is a challenging complication of abdominal typhoid with a high mortality
and difficult to manage. Delayed perforations following initial operative intervention is one of the rarer
complications of this disease, causing wound breakdown and open abdomen, resulting in fistula. We
present the management of a rare case, which presented with multiple perforations and multiple organ
system dysfunction then complicated post-operatively with multiple fistula and open abdomen.
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