Damage accumulation location under cyclic loading in the lumbar disc shifts from inner annulus lamellae to peripheral annulus with increasing disc degeneration

Qasim, Muhammad; Natarajan, Raghu N.; An, Howard S.; Andersson, Gunnar

doi:10.1016/j.jbiomech.2013.10.032

Cited by 51 publications

(69 citation statements)

References 63 publications

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“…Many numerical investigations [25,26,27,34,35,36] showed that the highest stresses and strains were located in the posterior and in the postero-lateral region of the AF. O’Connell et al showed by an MRI based set-up that in the human discs the strains are the highest in the posterior region of the annulus in all loading conditions [37].…”

Section: Discussionmentioning

confidence: 99%

“…It also allows to explore where the maximum stresses and strains are located and their entity, and their dependence by the degree of degeneration [22,23,24,25,26]. …”

Section: Introductionmentioning

confidence: 99%

“…However, finite element models mostly describe the human disc, therefore they cannot be used to investigate the experimental tests on animals [22,24,25,26,27,28]. To authors’ knowledge, few models of the ovine lumbar disc have been described in the literature.…”

Section: Introductionmentioning

confidence: 99%

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Numerical Prediction of the Mechanical Failure of the Intervertebral Disc under Complex Loading Conditions

et al. 2017

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Finite element modeling has been widely used to simulate the mechanical behavior of the intervertebral disc. Previous models have been generally limited to the prediction of the disc behavior under simple loading conditions, thus neglecting its response to complex loads, which may induce its failure. The aim of this study was to generate a finite element model of the ovine lumbar intervertebral disc, in which the annulus was characterized by an anisotropic hyperelastic formulation, and to use it to define which mechanical condition was unsafe for the disc. Based on published in vitro results, numerical analyses under combined flexion, lateral bending, and axial rotation with a magnitude double that of the physiological ones were performed. The simulations showed that flexion was the most unsafe load and an axial tensile stress greater than 10 MPa can cause disc failure. The numerical model here presented can be used to predict the failure of the disc under all loading conditions, which may support indications about the degree of safety of specific motions and daily activities, such as weight lifting.

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Section: Discussionmentioning

confidence: 99%

“…It also allows to explore where the maximum stresses and strains are located and their entity, and their dependence by the degree of degeneration [22,23,24,25,26]. …”

Section: Introductionmentioning

confidence: 99%

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Numerical Prediction of the Mechanical Failure of the Intervertebral Disc under Complex Loading Conditions

et al. 2017

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“…Results of the analysis of four intervertebral discs with different degenerated grades showed that the IDP is highest in flexion, and that IDP increases with the severity of degeneration [13]. The investigation of the processes that result in mechanical damage for different degenerated discs demonstrated that the number of cycles to failure sharply decreases with increasing degeneration and that the damages in healthy and moderately degenerated discs initiate at the posterior inner annulus and propagate outwards toward its periphery, whereas in serious degenerated case, damage initiates at the posterior outer annulus and propagates circumferentially [23].…”

Section: Introductionmentioning

confidence: 99%

Effects of resting modes on human lumbar spines with different levels of degenerated intervertebral discs: a finite element investigation

Fan

Gong

Qiu

et al. 2015

BMC Musculoskelet Disord

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Background: The negative effect of long-term working load on lumbar is widely known. However, insertion of different resting modes on long-term working load, and its effects on the lumbar spine is rarely studied. The purpose of this study was to investigate the biomechanical responses of lumbar spine with different levels of degenerated intervertebral discs under different working-resting modes. Methods: Four poroelastic finite element models of lumbar spinal segments L2-L3 with different grades of disc degeneration were developed. Four different loading conditions represented four different resting frequencies, namely, no rest, one-time long rest, three-time moderate rests, and five-time short rests, on the condition that the total resting time was the same except in the no rest mode. Loading amplitudes of diurnal activities included 100 N, 300 N, and 500 N. Results: With increasing resting frequency, the axial effective stress and fluid loss decreased, whereas the pore pressure and radial displacement increased. Under different resting frequencies, the changing rate of each biomechanical parameter was different. Conclusions: Under a situation of fixed total resting time, high resting frequency was advisable. If sufficient resting frequency was unavailable for healthy people as well as patients with mildly and moderately degenerated intervertebral discs, they could similarly benefit from relatively less resting frequencies. However, one-time rest will not be useful in cases where intervertebral discs were seriously degenerated. Reasonable working-resting modes for different degrees of disc degeneration, which could assist patients achieve a better restoration, were provided in this study.

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“…This framework has already been applied to bone (Zysset and Curnier, 1996;Garcia et al, 2009), articular cartilage (Hosseini et al, 2014), intervertebral disc (Qasim et al, 2014), and other soft tissues (Bernick et al, 2011;Balzani et al, 2012;Calvo et al, 2009) work, an orthodontic tooth movement model is developed and applied to two representative types of tooth movements.…”

Section: Damage-like Biological Application: a Model For Orthodontic mentioning

confidence: 99%

A generic anisotropic continuum damage model integration scheme adaptable to both ductile damage and biological damage-like situations

Mengoni¹,

Ponthot²

2015

International Journal of Plasticity

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This paper aims at presenting a general versatile time integration scheme applicable to anisotropic damage coupled to elastoplasticity, considering any damage rate and isotropic hardening formulations. For this purpose a staggered time integration scheme in a finite strain framework is presented, together with an analytical consistent tangent operator. The only restrictive hypothesis is to work with an undamaged isotropic material, assumed here to follow a J 2 plasticity model. The only anisotropy considered is thus a damage-induced anisotropy.The possibility to couple any damage rate law with the present algorithm is illustrated with a classical ductile damage model for aluminium, and a biological damage-like application. The later proposes an original bone remodelling law coupled to trabecular bone plasticity for the simulation of orthodontic tooth movements. All the developments have been considered in the framework of the implicit non-linear finite element code Metafor (developed at the LTAS/MN 2 L, University of Liège, Belgium -www.metafor.ltas.ulg.ac.be).

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Damage accumulation location under cyclic loading in the lumbar disc shifts from inner annulus lamellae to peripheral annulus with increasing disc degeneration

Cited by 51 publications

References 63 publications

Numerical Prediction of the Mechanical Failure of the Intervertebral Disc under Complex Loading Conditions

Numerical Prediction of the Mechanical Failure of the Intervertebral Disc under Complex Loading Conditions

Effects of resting modes on human lumbar spines with different levels of degenerated intervertebral discs: a finite element investigation

A generic anisotropic continuum damage model integration scheme adaptable to both ductile damage and biological damage-like situations

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