Dairy propionibacteria as human probiotics: A review of recent evidence

Abstract

Probiotics have been the subject of intensive research, mainly focusing on bifidobacteria and lactic acid bacteria. However, there is evidence that dairy propionibacteria also display probiotic properties, which as yet have been underestimated. The aim of this paper is to review recent data which report probiotic characteristics of dairy propionibacteria and to distinctly organise them based on the experimental strategy employed: ranked from in vitro evidence to in vivo trials, which is a new approach. In addition to the selection criteria for probiotics in areas such as food safety, technological and digestive stress tolerance, many potential health benefits have been described which include modulation of microbiota and metabolic activity in the gut, modulation of intestinal motility and absorption, impact on intestinal inflammation, modulation of the immune system and potential modulation of risk factors for cancer development. The robust nature of dairy propionibacteria towards technological stresses should allow their future use in various fermented probiotic foods. Among the probiotic properties of dairy propionibacteria described in the literature, some of these properties are different from those reported for bifidobacteria and lactic acid bacteria. However, supplementation with dairy propionibacteria in randomised, placebo-controlled, double

Dairy Propionibacteria: Less Conventional Probiotics to Improve the Human and Animal Health

“…At present, no cases of sickness or toxicity after the ingestion of dairy propionibacteria have been reported [122] neither for humans (for a review of human trials see [123]) nor for animals [124][125][126]. In fact, it has been reported that propionibacteria did not translocate to blood, liver or spleen and no adverse effects on body weight gain and general health status was observed after short [124,127] and long terms [125] administration of strains of Propionibacterium acidipropionici, P. freudenreichii and P. jensenii, respectively.…”

Promising Immunomodulatory Effects of Selected Strains of Dairy Propionibacteria as Evidenced In Vitro and In Vivo

“…Consumption of fermented products has an impact on immune system function (25), and the bacterial content of these products is responsible for immunomodulation (6,10). Dairy propionibacteria display various probiotic properties either similar to or distinct from those reported for probiotic bifidobacteria and lactic acid bacteria (3). Although an anti-inflammatory potential of a few dairy propionibacterium strains was occasionally suggested in vitro (15) or in animals (22,24,31), no reliable observation was established in terms of strain variability and of specific mechanisms involved.…”

Probiotic Properties and Biotechnological Potential of Propionic Acid Bacteria

“…пропионовая кислота, образованная в цикле ВудаВеркмана, транспор тируется в печень и включается в процесс глюконеогенеза и синтеза биогенных аминов, улучшает микроциркуляцию в слизистой кишечника и поддерживает в ней метаболические процессы, блокирует прикрепление к колоноцитам условнопатогенной микробиты, и в тоже время стимулирует рост анаэробных бактерий нормальной микробиоты ЖКТ [11,17,18]. [6][7][8][9][10][11][12][13][14][15] Витамин В 12 является необычным в отношении своего происхождения. Практически все витамины могут быть выделены из разнообразных растений или животных но, ни одно растение или животное не способно производить витамин B 12 .…”

“…На образование витамина благоприятное влияние оказывает наличие молочной кислоты, создавая элективностъ условий [5,11,18].…”

“…С. [6][7][8][9][10][11][12][13][14][15] восстановительный потенциал организма, эти процессы приводят к снижению количества мутаций [2,8].…”