Daily Mean Temperature and Clinical Kidney Stone Presentation in Five U.S. Metropolitan Areas: A Time-Series Analysis

Tasian, Gregory E.; Pulido, Jose E.; Gasparrini, Antonio; Saigal, Christopher S.; Horton, Benjamin P.; Landis, J. Richard; Madison, Roger D.; Keren, Ron

doi:10.1289/ehp.1307703

Cited by 105 publications

(97 citation statements)

References 30 publications

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“…First, our observations are on the basis of data from one state. It is possible that the absolute incidence of nephrolithiasis is higher in South Carolina than the rest of the United States because of the higher prevalence of nephrolithiasis in the Southeast (34,35). However, the trends that we observed are consistent with increases in nephrolithiasis frequency reported in prior studies from other areas in the United States (1,7,912,13,36).…”

Section: Discussionsupporting

confidence: 83%

“…However, detection bias is unlikely, because computed tomography use stabilized among young adults and decreased among children beginning in the 2000s (38,39). Additionally, although climate change may affect future nephrolithiasis prevalence (40) and hot and cold temperatures are associated with increased risk of stone presentation (35), any environmental changes over the study period would not substantively affect nephrolithiasis incidence. It is also likely that factors other than increasing prevalence of obesity and diabetes (41) account for the increasing incidence of nephrolithiasis that we observed, particularly because obesity may not be associated with increased risk for kidney stones among children or adolescents (42).…”

Section: Discussionmentioning

confidence: 99%

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Annual Incidence of Nephrolithiasis among Children and Adults in South Carolina from 1997 to 2012

Tasian

Ross

Song³

et al. 2016

Clinical Journal of the American Society of Nephrology

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Background and objectives The prevalence of nephrolithiasis in the United States has increased substantially, but recent changes in incidence with respect to age, sex, and race are not well characterized. This study examined temporal trends in the annual incidence and cumulative risk of nephrolithiasis among children and adults living in South Carolina over a 16-year period.Design, setting, participants, & measurements We performed a population-based, repeated cross-sectional study using the US Census and South Carolina Medical Encounter data, which capture all emergency department visits, surgeries, and admissions in the state. The annual incidence of nephrolithiasis in South Carolina from 1997 to 2012 was estimated, and linear mixed models were used to estimate incidence rate ratios for age, sex, and racial groups. The cumulative risk of nephrolithiasis during childhood and over the lifetime was estimated for males and females in 1997 and 2012.Results Among an at-risk population of 4,625,364 people, 152,925 unique patients received emergency, inpatient, or surgical care for nephrolithiasis. Between 1997 and 2012, the mean annual incidence of nephrolithiasis increased 1% annually from 206 to 239 per 100,000 persons. Among age groups, the greatest increase was observed among 15-19 year olds, in whom incidence increased 26% per 5 years (incidence rate ratio, 1.26; 95% confidence interval, 1.22 to 1.29). Adjusting for age and race, incidence increased 15% per 5 years among females (incidence rate ratio, 1.15; 95% confidence interval, 1.14 to 1.16) but remained stable for males. The incidence among blacks increased 15% more per 5 years compared with whites (incidence rate ratio, 1.15; 95% confidence interval, 1.14 to 1.17). These changes in incidence resulted in doubling of the risk of nephrolithiasis during childhood and a 45% increase in the lifetime risk of nephrolithiasis for women over the study period.Conclusions The incidence of kidney stones has increased among young patients, particularly women, and blacks.

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Section: Discussionsupporting

confidence: 83%

Section: Discussionmentioning

confidence: 99%

Annual Incidence of Nephrolithiasis among Children and Adults in South Carolina from 1997 to 2012

Tasian

Ross

Song³

et al. 2016

Clinical Journal of the American Society of Nephrology

Self Cite

206

130

View full text Add to dashboard Cite

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“…Additionally, investigations have shown an association between hot and cold days and an increased risk of kidney stones (34). Presumably, the effect of temperature on stone risk is mediated by dehydration from insensible water loss.…”

Section: Environmental Exposuresmentioning

confidence: 99%

Urinary Stone Disease: Advancing Knowledge, Patient Care, and Population Health

Scales

Tasian

Schwaderer

et al. 2016

CJASN

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130

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Expanding epidemiologic and physiologic data suggest that urinary stone disease is best conceptualized as a chronic metabolic condition punctuated by symptomatic, preventable stone events. These acute events herald substantial future chronic morbidity, including decreased bone mineral density, cardiovascular disease, and CKD. Urinary stone disease imposes a large and growing public health burden. In the United States, 1 in 11 individuals will experience a urinary stone in their lifetime. Given this high incidence and prevalence, urinary stone disease is one of the most expensive urologic conditions, with health care charges exceeding $10 billion annually. Patient care focuses on management of symptomatic stones rather than prevention; after three decades of innovation, procedural interventions are almost exclusively minimally invasive or noninvasive, and mortality is rare. Despite these advances, the prevalence of stone disease has nearly doubled over the past 15 years, likely secondary to dietary and health trends. The NIDDK recently convened a symposium to assess knowledge and treatment gaps to inform future urinary stone disease research. Reducing the public health burden of urinary stone disease will require key advances in understanding environmental, genetic, and other individual disease determinants; improving secondary prevention; and optimal population health strategies in an increasingly cost-conscious care environment.

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“…21 Higher temperatures have also been associated with clinical kidney stone presentation, with daily mean temperature of 30 C associated with significantly increased episodes compared with daily mean temperature of 10 C in 4 major metropolitan areas studied (Atlanta, Chicago, Dallas, and Philadelphia). 22 Mathematical modeling has been used to examine the association between geography and stone incidence. Brikowski and others 23 used predictions based on climate modeling to show a concentration of greatest increase in nephrolithiasis over the next century to be in California, Texas, Florida, the eastern United States, and a geographic band stretching from Kansas to Kentucky-states that on the whole are affected by much warmer temperatures than the rest of the country.…”

Section: Urine and Stone Compositionmentioning

confidence: 99%