Daily grape juice consumption reduces oxidative DNA damage and plasma free radical levels in healthy Koreans

Park, Yoo Kyoung; Park, Eunju; Kim, Jung-Shin; Kang, Myung‐Hee

doi:10.1016/s0027-5107(03)00109-x

Cited by 134 publications

(70 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It is known that alcohol has pro-oxidant effects. Studies performed with dealcoholized wine, grapes, and GSE have shown strong antioxidant effects, indicating that the polyphenol content contributes critically to the antioxidant abilities of wine (Young et al 2000, Abu-Amsha Caccetta et al 2001, Bagchi et al 2002, Durak et al 2002, O'Byrne et al 2002, Park et al 2003, Vigna et al 2003, Ko et al 2005, Zern et al 2005, Castilla et al 2006. The antioxidant effects of red wine and of its major polyphenols have been demonstrated with in vitro systems, in cell culture, and in human subjects (Soleas et al 1997, Fernandez-Pachon et al 2006, Modun et al 2008.…”

Section: Antioxidant Effectsmentioning

confidence: 99%

Wine and Health: A Review

Guilford

Pezzuto

2011

Am. J. Enol. Vitic.

166

View full text Add to dashboard Cite

Abstract:As indicated by epidemiological studies, regular and moderate wine consumption, particularly red wine, has been associated with health benefits. Clinical studies and work performed with animal models indicate that wine may protect against cardiovascular disease, atherosclerosis, hypertension, certain types of cancer, type 2 diabetes, neurological disorders, and metabolic syndrome. The mechanism of action has been attributed to antioxidant, lipid regulating, and anti-inflammatory effects. A variety of wine constituents have been studied in various disease models. Both the alcoholic and polyphenolic components of wine are believed to contribute to these beneficial effects. As wine is a complex mixture, it is likely that a multitude of chemical constituents, as well as their metabolites, work synergistically to impact human health. In sum, although wine drinking may be contraindicated in certain individuals, in healthy people, regular consumption of moderate amounts of wine may protect against certain chronic health conditions.

show abstract

Section: Antioxidant Effectsmentioning

confidence: 99%

Wine and Health: A Review

Guilford

Pezzuto

2011

Am. J. Enol. Vitic.

166

View full text Add to dashboard Cite

show abstract

“…Natural antioxidants present in the grapes include anthocyanins and others flavonoids, which are ubiquitously distributed in the vegetable kingdom as secondary plant metabolites (Paganda and RiceEvans 1997). Many studies have suggested that ingesting phenolic compounds can help prevent diseases (Scalbert and Williamson 2000;Park et al 2003;Houston et al 2007;Spormann 2008;Russell et al 2009). Since grape juice has almost three times the total polyphenolic concentration of orange or grapefruit, there are large differences between the classes of juice flavonoids (Russell et al 2009).…”

Section: Introductionmentioning

confidence: 99%

Production of grape juice powder obtained by freeze-drying after concentration by reverse osmosis

Gurak

Cabral

Rocha-Leão

2013

Braz. arch. biol. technol.

View full text Add to dashboard Cite

show abstract

“…Moderation is considered one drink (defined as 12 ounces of beer, 4 ounces of wine, 1.5 ounces of 80-proof spirits, or 1 ounce of 100-proof spirits) per day for women and two drinks per day for men (6). Some short-term research suggests that 100 percent purple grape juice may be an alcoholfree alternative to red wine for those interested in both the cardiovascular and anticancer effects of this beverage; however, a reduction in development of chronic disease and mortality due to consumption of grape juice has yet to be confirmed (7,8). If you do choose to consume purple grape juice, remember to follow the Dietary Guidelines and limit juice consumption by choosing whole fruit for the majority of your daily fruit servings (6).…”

Section: Publication 8318mentioning

confidence: 99%

Nutrition and Health Info Sheet: Catechins

Heneman¹,

Zidenberg‐Cherr²

2008

View full text Add to dashboard Cite

What are catechins?Catechins are phytochemical compounds found in plant-based foods and beverages. Based on their structure, catechins are classified as flavanols and include the following compounds: catechin, epicatechin, epigallocatechin, epicatechin gallate, and epigallocatechin gallate. High concentrations of catechin can be found in red wine, broad beans, black grapes, apricots, and strawberries. Epicatechin concentrations are high in apples, blackberries, broad beans, cherries, black grapes, pears, raspberries, and chocolate. Finally, epigallocatechin, epicatechin gallate, and epigallocatechin gallate are found in high concentrations in both black and green tea (1).What is the catechin content of some common foods? (2) Are there beneficial effects associated with consumption of catechins?Consumption of catechins has been associated with a variety of beneficial effects, including increased plasma antioxidant activity (ability of plasma to scavenge free radicals), brachial artery dilation (blood vessel expansion), fat oxidation, and resistance of LDL to oxidation (1).There seems to be a lot of media hype around red wine, chocolate, and tea. Are these really "super foods"?As shown in the table above, red wine, chocolate, and tea are all high in catechins, in addition to a variety of other polyphenolic compounds. Below is a summary of the research on the effects of consuming these foods: Red wineStudies have investigated the relationship between consumption of red wine and susceptibility to chronic diseases such as lung cancer, prostate cancer, and cardiovascular disease. • Cardiovascular Disease: Consumption of red wine is associated with a reduction in endothelin-1 (a molecule involved in blood pressure regulation), a reduction in myocardial ischemic reperfusion injury (an injury to the heart when blood is returned to the organ after a period of restriction), increased HDL, decreased platelet aggregation (clumping), increased fibrinolysis (breakdown of a clot), and increased antioxidant activity (3).• Lung Cancer: In one recent investigation, consumption of red wine was associated with a reduced risk of lung cancer in comparison to those who did not consume any red wine (4).• Prostate Cancer: In middle-aged men, a 6 percent decrease in risk of prostate cancer has been observed for every glass of red wine consumed per week (5).• Conclusions: In light of this research, the American Heart Association does not recommend consumption of alcohol to reduce risk of cardiovascular disease and the American Cancer Society recommends limiting consumption of alcoholic beverages. If adults choose to drink alcoholic beverages, the Dietary Guidelines 2005 recommend they do so in moderation. Moderation is considered one drink (defined as 12 ounces of beer, 4 ounces of wine, 1.5 ounces of 80-proof spirits, or 1 ounce of 100-proof spirits) per day for women and two drinks per day for men (6). Some short-term research suggests that 100 percent purple grape juice may be an alcoholfree alternative to red wine for those interested ...

show abstract

Daily grape juice consumption reduces oxidative DNA damage and plasma free radical levels in healthy Koreans

Cited by 134 publications

References 42 publications

Wine and Health: A Review

Wine and Health: A Review

Production of grape juice powder obtained by freeze-drying after concentration by reverse osmosis

Nutrition and Health Info Sheet: Catechins

Contact Info

Product

Resources

About