Daily associations with cannabis use and sleep quality in anxious cannabis users

Bidwell, L. Cinnamon; Sznitman, Sharon R.; Martin‐Willett, Renée; Hitchcock, Leah N.

doi:10.1080/15402002.2023.2217969

Cited by 4 publications

(2 citation statements)

References 96 publications

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“…Interestingly, the highest perceived quality of sleep was noted by the respondents who ingested Cannabis products containing high CBD concentration. 114 …”

Section: What Do We Know About Clinically Important Cannabinoids?mentioning

confidence: 99%

“…Interestingly, the highest perceived quality of sleep was noted by the respondents who ingested Cannabis products containing high CBD concentration. 114 When THC is used for a short period, it shows certain effects on sleep. Studies conducted on rabbits and cats suggest that these effects include improved sleep continuity, reduced sleep onset latency (SOL), increased overall sleep duration (OSD), and decreased wake after sleep onset (WASO).…”

Section: Cannabinoids In the Treatment Of Sleep Disordersmentioning

confidence: 99%

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How Biodegradable Polymers Can be Effective Drug Delivery Systems for Cannabinoids? Prospectives and Challenges

Sobieraj,

Strzelecka,

Sobczak

et al. 2024

IJN

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Cannabinoids are compounds found in and derived from the Cannabis plants that have become increasingly recognised as significant modulating factors of physiological mechanisms and inflammatory reactions of the organism, thus inevitably affecting maintenance of homeostasis. Medical Cannabis popularity has surged since its legal regulation growing around the world. Numerous promising discoveries bring more data on cannabinoids’ pharmacological characteristics and therapeutic applications. Given the current surge in interest in the medical use of cannabinoids, there is an urgent need for an effective method of their administration. Surpassing low bioavailability, low water solubility, and instability became an important milestone in the advancement of cannabinoids in pharmaceutical applications. The numerous uses of cannabinoids in clinical practice remain restricted by limited administration alternatives, but there is hope when biodegradable polymers are taken into account. The primary objective of this review is to highlight the wide range of indications for which cannabinoids may be used, as well as the polymeric carriers that enhance their effectiveness. The current review described a wide range of therapeutic applications of cannabinoids, including pain management, neurological and sleep disorders, anxiety, and cancer treatment. The use of these compounds was further examined in the area of dermatology and cosmetology. Finally, with the use of biodegradable polymer-based drug delivery systems (DDSs), it was demonstrated that cannabinoids can be delivered specifically to the intended site while also improving the drug’s physicochemical properties, emphasizing their utility. Nevertheless, additional clinical trials on novel cannabinoids’ formulations are required, as their full spectrum therapeutical potential is yet to be unravelled.

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“…Interestingly, the highest perceived quality of sleep was noted by the respondents who ingested Cannabis products containing high CBD concentration. 114 …”

Section: What Do We Know About Clinically Important Cannabinoids?mentioning

confidence: 99%

Section: Cannabinoids In the Treatment Of Sleep Disordersmentioning

confidence: 99%

How Biodegradable Polymers Can be Effective Drug Delivery Systems for Cannabinoids? Prospectives and Challenges

Sobieraj,

Strzelecka,

Sobczak

et al. 2024

IJN

View full text Add to dashboard Cite

show abstract

Cannabis‐infused foods: Phytonutrients, health, and safe product innovations

Fordjour,

Manful,

Khalsamehta

et al. 2024

Comp Rev Food Sci Food Safe

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Cannabis‐infused foods are currently on the rise in markets all around the world. Meanwhile, there are concerns over the health implications for consumers. Studies have explored the therapeutic potential and nutritional and economic benefits of cannabis usage. Yet, the phytonutrients, processing methods, and health implications of cannabis‐infused foods have not been well explored. This review evaluates existing evidence on the nutritional, processing, safety, and phytonutrient composition of cannabis‐infused food products and their medicinal and functional prospects. Cannabis seeds contain the highest amount of dietary nutrients, while flowers contain the highest amount of bioactive constituents. Oils, butter, seeds, flowers, and leaf extracts are the plant forms currently incorporated into food products such as beverages, baked products, cooking ingredients, functional foods, nutraceuticals, and nootropics. Cannabis‐infused foods have been found to offer therapeutic benefits for pain management, brain function, gut health, and certain cancers. Findings also show significant constraints associated with cannabis‐infused foods regarding dosage guidelines, limited research, efficacy, and long‐term health effects on consumers. This is further worsened by the lack of policies that regulate the industry. To realize the full potential of cannabis use in the food and health industries and in research, regulatory guidelines are needed to control dosages and improve its efficient use in these industries. This will go a long way to ensure the safety of cannabis users and enhance responsible production, marketing, and distribution.

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Daily diary study of associations between alcohol, cannabis, co‐use and sleep quality in individuals with intentions to use cannabis to cope with anxiety

Sznitman,

Martin‐Willett,

et al. 2023

Drug and Alcohol Review

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IntroductionSleep problems and anxiety conditions are common comorbidities and may be influenced by cannabis and alcohol use. This study examined daily within‐person variation in subjective sleep quality among individuals with anxiety symptoms after cannabis or alcohol were used alone, and after co‐use.MethodsA total of 347 individuals with intentions to use cannabis to cope with anxiety reported their cannabis and alcohol use in the previous 24 h and their previous nights' sleep quality for 30 consecutive days. Mixed‐effects models examined whether the within‐person daily variation in use of cannabis and alcohol (alone and co‐use) was associated with subjective sleep quality. Models also examined whether daily cannabis and alcohol use associations with sleep were moderated by frequency of cannabis, alcohol and co‐use during the study period.ResultsCompared to non‐use, participants reported better sleep after cannabis‐use‐only and after co‐use, but not after alcohol‐use‐only. People who more frequently use alcohol and cannabis reported sleeping better after cannabis‐use‐only days compared to those who use cannabis and alcohol less frequently.Discussion and ConclusionsThe study's utilisation of naturalistic data among individuals with anxiety symptoms replicated previously reported experimental findings among individuals without sleep and anxiety problems that overall, cannabis is associated with higher subjective sleep quality. The results expand upon other research to suggest that more frequent use of alcohol and cannabis may moderate daily associations of cannabis use and sleep, potentially through pharmacokinetics and cross‐sensitisation.

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Daily associations with cannabis use and sleep quality in anxious cannabis users

Cited by 4 publications

References 96 publications

How Biodegradable Polymers Can be Effective Drug Delivery Systems for Cannabinoids? Prospectives and Challenges

How Biodegradable Polymers Can be Effective Drug Delivery Systems for Cannabinoids? Prospectives and Challenges

Cannabis‐infused foods: Phytonutrients, health, and safe product innovations

Daily diary study of associations between alcohol, cannabis, co‐use and sleep quality in individuals with intentions to use cannabis to cope with anxiety

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