Dacron as Arterial Prosthetic Material: Nature, Properties, Brands, Fate and Perspectives

Abstract

Dacron graft prostheses are routinely implanted to overcome impairment of arterial flow to distal tissues. Many different fabric configurations have been developped and evaluated. Unfortunately, after implantation the flow surface of any graft persists as a fibrinous lining. No human specimen has a commonly ingrown extension of tissue exceeding some millimeters in length. Full wall healing and endothelialization of arterial prosthesis is a goal that must be pursued intensively because it seems that the goal is attainable.

Analysis of polyhydroxyethyl methacrylate coatings on polyethylene terephthalate fabric substrates for cardiovascular prosthetic applications

“…The outer layer surrounding the graft was a thick, dense layer composed mainly of fibrous connective tissue. In Figure 65a theses have established the sequence of events for the healing of woven prostheses exposed to flowing blood (Stewart et al, 1975;Guidoin et al, 1975Guidoin et al, , 1977. Our studies compared well with their observations.…”

“…(molecular weight 192). Industrially, the polymer is prepared by a three (Guidoin et al, 1977). Skelton (1974) suggests that these additives could profoundly affect the fiber's performance under implant conditions but very few complaints have been listed and the quality of commercially available fabrics for pros thetic use has not been discussed.…”

Interventionelle Therapie von Karotisaneurysmen mit Stents

“…Eine Erkl~irung fª die Induktion einer 6rtlichen Toxizit~it k6nnten die Produktionsvorg~inge bei der Polyesterherstellung sein, bei der Salze, Schwermetalle, stickstoffhaltige aromatische organische Verbindungen und Antioxidationsmittel verwendet werden. Diese werden m6glicherweise im K6rper freigesetzt und verursachen lokale Reaktionen [9]. Die ron uns bei allen Pr~ipara-ten mit einem ummantelten Stent beobachteten, wechselnd starken, ª aber deutlichen Entzª dungsreaktionen mit reichlich Granulozyteninfiltrationen um das Polyestermaterial erh~rten den Verdacht, dar5 der Polyestermantel des Stents fª den ungª gen Verlauf verantwortlich zu machen ist.…”

Polyethylene Terephthalate and Polyurethane Coatings for Endovascular Stents: Preliminary Results in Canine Experimental Arteriovenous Fistulas

“…However, perivascular and systemic inflammatory reactions have been reported (8,9), which seem to be responsible for poor short-term patency rates in experimental studies (9). Not yet clear is whether these reactions are directed against the specific polyester itself or manufacturing-related components (10,11). Polyurethane proved to be successful in the preparation of biomaterials with low bacterial adherence and improved biocompatibility (12).…”