D40. Effects of Lymphaticovenular Anastomosis in Contralateral Leg in Patients with Acquired Bilateral Leg Lymphedema

Lymphovenous Anastomosis for the External and Internal Types of Head and Neck Lymphedema: A Case Series and Preliminary Clinical Results

“…28 In 2023, Chen et al also noted that the impact of LVA extended beyond the anatomic region where it was performed. 29 Both above findings might imply the potential systemic effect brought by LVA. In 2018, Mesquita et al demonstrated that using vascular endothelial growth factor C to treat aged mice could improve meningeal lymphatic drainage, enhancing learning and memory performance.…”

Rewiring the Brain – the Next Frontier in Supermicrosurgery

“…2 The three-dimensional topography of the external ear accurately reflects the shape of the internal cartilaginous skeleton. 3 Reproducing anatomical and structural details of the external ear is a challenge for any plastic surgeon and requires a high level of surgical skill and training to fulfill the patient's expectation. Surgical simulation allows development of these skills, reducing mistakes, shortening surgical time, and improving results in vivo.…”

“…1 Our research on lymphedema reconstruction of the arms, legs, and trunk led us to observe the catchment effect 2 and systemic effect. 3 These effects demonstrate that the lymphatic system responds to surgical treatment as a unified organ, which means that lymphatic surgery remains effective whether it is done at the problem site or elsewhere. Combining these observations with the discovery of glymphatic 4 and meningeal lymphatic 5 dysfunction in Alzheimer disease and other neurodegenerative proteinopathies, we hypothesized that extracranial supermicrosurgical lymphatic reconstruction may "de-clog" the brain to improve the above conditions.…”