“…Because of the great variety of nuclear transmutation reactions (115,116) which can be brought about by bombardment with deuterons, protons, and alpha particles, it is frequently possible to produce a desired radioisotope by several different types of nuclear reactions. In determining the particular reaction to be employed, several factors must be considered, including (1) the yield of the desired radioisotope, (#) the relative yields of the possible concurrent side reactions, (3) the problem of the ultimate chemical separations of the desired product, and (4) the chemical and physical limitations which must necessarily be imposed in the choice of target material for charged-particle bombardment. Considerations 1 and 2 are discussed below and 3 and 4 are covered in the section on separation procedures.…”