D-mannitol sensor based on molecularly imprinted polymer on electrode modified with reduced graphene oxide decorated with gold nanoparticles

Abstract

An electrochemical sensor for D-mannitol based on molecularly imprinted polymer on electrode modified with reduced graphene oxide decorated with gold nanoparticles was developed in this present work. The sensor was constructed for the first time via the electropolymerization of o-phenylenediamine (o-PD) over a surface containing reduced graphene oxide (RGO) and gold nanoparticles (AuNP) in the presence of D-mannitol molecules. The surface modification with AuNP/RGO-GCE facilitated the charge transfer processes of [Fe(CN)], which was used as an electrochemical probe. It also contributed meaningfully towards the increase in the surface/volume ratio, creating more locations for imprinting, and providing greater sensitivity to the sensor. The MIP/AuNP/RGO-GCE sensor was characterized by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), scanning electron microscope (SEM), atomic force microscope (AFM) and X-ray Photoelectron Spectroscopy (XPS). Important parameters that exert control over the performance of the molecularly imprinted sensor (such as number of cycles, pH, monomer and template concentration and extraction and rebinding conditions) were investigated and optimized. The imprinting factor was 4.9, showing greater response to the D-mannitol molecule compared to the interfering molecules. The limit of detection, limit of quantification and amperometric sensitivity were 7.7×10molL, 2.6×10molL and 3.9×10µALmol (n=3) respectively. The MIP/AuNP/RGO-GCE sensor was successfully applied towards the selective determination of D-mannitol in sugarcane vinasse, thus making it, in essence, a valuable tool for the accurate and reliable determination of this molecule.

Electrosynthesis of Molecularly Imprinted Poly‐o‐phenylenediamine on MWCNT Modified Electrode for Selective Determination of Meldonium

“…The imprinted factor (f), (f equals to the ratio of the decrease of the current response of MEL‐imp/MWCNT/PRE (ΔI MIP ) and N‐imp/MWCNT/PRE (ΔI NIP )) of MEL , LYC, GLU, HIS, ARG and GLY were calculated as 7.6, 1.1, 1.03, 1.0, 1.1, and 1.5, respectively. The higher imprinted factor indicates the higher response of a sensor to the target molecule compared to the interfering molecules . In addition, when the imprinted factor of an electrode equals to 1.0 it means that the electrode has not an imprinting property and the possible interferences does not affect the detection .…”

Microscale‐Patterned Graphene Electrodes for Organic Light‐Emitting Devices by a Simple Patterning Strategy

“…The chemical composition between graphene and SU‐8 was analyzed by high‐resolution X‐ray photoelectron spectroscopy (XPS) to investigate the chemical bonding related to O 1s and C 1s ( Figure ). The O 1s spectra of SU‐8 and graphene/SU‐8 (Figure a,b) can be de‐convoluted into different functional groups of CO (532.6 eV), OCO (533.9 eV), and CO (531.5 eV), while the unique CO bonds just appears in graphene/SU‐8 system. To further confirm that CO bonds derive from the bonding between graphene and SU‐8 rather than graphene itself, the C1s XPS spectra of graphene and graphene/SU‐8 were investigated (Figure c,d).…”

Recent Advances in Electrochemical Sensors Based on Molecularly Imprinted Polymers and Nanomaterials

“…Some applications of these nanohybrid materials for the development of highly sensitive and selective electrochemical sensors are cited in this review . It should be noticed that the AuNPs/MIPs nanohybrid materials are also combined with other kinds of nanoparticles such as graphene, carbon nanotubes and carbonaceous materials to develop novel sensing strategies as indicated in Table .…”