2023
DOI: 10.1016/bs.acc.2023.02.006
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D-dimer testing: A narrative review

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Cited by 8 publications
(7 citation statements)
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“…However, no significant change was observed in D-dimer concentration when the sample was stored at 4 or -20°C for 10 days (Kiefer et al, 2018). It is reported that the d-dimer concentration wasn't affected by lithium heparin and sodium citrate (Wauthier et al, 2023). When a comparison was made for d-dimer concentration in dog blood collected in EDTA and sodium citrate, the concentration of d-dimer was observed to be elevated (Ke et al, 2023).…”
Section: D-dimer Concentrationmentioning
confidence: 95%
See 1 more Smart Citation
“…However, no significant change was observed in D-dimer concentration when the sample was stored at 4 or -20°C for 10 days (Kiefer et al, 2018). It is reported that the d-dimer concentration wasn't affected by lithium heparin and sodium citrate (Wauthier et al, 2023). When a comparison was made for d-dimer concentration in dog blood collected in EDTA and sodium citrate, the concentration of d-dimer was observed to be elevated (Ke et al, 2023).…”
Section: D-dimer Concentrationmentioning
confidence: 95%
“…When HbA1c value remains stable when measured from blood collected with sodium heparin, lithium heparin, EDTA, sodium citrate, and sodium fluoride, these anticoagulants do not affect HbA1c value. This is because the RBCs are lysed before the test is conducted (Ke et al, 2023;Kiefer et al, 2018;Wauthier et al, 2023).…”
Section: Changes In Blood Glucose Concentrationmentioning
confidence: 99%
“…D-dimer values tend to increase physiologically with ageing, in pregnancy and the postpartum period (up to 6 weeks after delivery), and in renal insufficiency. 38 D-dimer levels increase following a VTE event. As mentioned, to avoid unnecessary imaging testing, age-adjusted cutoffs have been proposed (age  10 μg/L, in patients aged >50 years) excluding PE and recently, a pregnancy-adapted algorithm has also been validated.…”
Section: Venous Thromboembolismmentioning
confidence: 97%
“…Depending on the assay employed, D-dimer tests may be classified as either high-sensitivity (>95%) and lowspecificity (<40%), or moderate-sensitivity (80-94%) and high-specificity (up to 70%). 38 Highly sensitive D-dimer testing is recommended for populations with low ( 5%) or intermediate ($20%) clinical probability of lower extremity DVT, as this assay exhibits outstanding negative predictive value (NPV) in patients with low probability of DVT. The risk of false negatives is contingent upon the prevalence of the disease within the studied population, which is determined by the clinician's assessment of clinical probability.…”
Section: Venous Thromboembolismmentioning
confidence: 99%
“…Other studies have shown that elevated d-dimer levels are also predictive of mortality in the context of peripheral artery disease (PAD) patients ( 1 ). Nevertheless, d-dimer levels have not yet been incorporated in guidelines for cardiovascular disease (CVD) management, although validated commercial assays are widely available already for a long time ( 2 ).…”
mentioning
confidence: 99%