D-A-π-D Synthetic approach for thienyl chalcones – NLO – a structure activity study

(E)-1-(5-Chlorothiophen-2-yl)-3-(2,4-dimethylphenyl)prop-2-en-1-one

“…The most commonly employed method for the synthesis of chalcones involves the condensation of an aromatic aldehyde and an aromatic ketone in the presence of aqueous alkaline bases (Mahapatra et al, 2015). In view of the broad spectrum of applications associated with chalcones and as a part of our ongoing work on such molecules (Tejkiran et al, 2016), we report here the synthesis and crystal structure of the title compound.…”

(E)-1-(1,3-Benzodioxol-5-yl)-3-(2,4,5-trimethoxyphenyl)prop-2-en-1-one

“…They have been efficiently employed as precursors in the syntheses of biologically potent benzothiazepines (Manjunath et al, 2014). In view of diversified applications of chalcones and as a part of our ongoing work on such molecules (Tejkiran et al, 2016), we report herein the synthesis and crystal structure of the title compound.…”

(E)-1-(1,3-Benzodioxol-5-yl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one

“…Chalcones and their derivatives demonstrate a wide range of biological activities, such as antioxidant, antifungal, antibacterial, cardioprotective. In view of the broad spectrum of applications associated with chalcones and as a part of our ongoing work on such molecules (Tejkiran et al, 2016;Naveen et al, 2016a), we report herein on the synthesis and crystal structure of the title compound. The molecule (Fig.…”