This article analyses and compares the influence of the Hungarian, Polish and Lithuanian Presidencies of the Council of the European Union (taking place between 2011 and 2013) on the Union's policies towards the countries of the Eastern Partnership -Belarus, Ukraine, Moldova, Georgia, Armenia and Azerbaijan. The influence of the Presidencies is compared through qualitative comparative analysis (QCA), which aims to identify necessary and sufficient conditions for influence to occur. The results show that there is only one necessary condition for the Presidency to exert influence, that is, the issue should be highly salient to the incumbent Member State. The absence of any other condition for influence does as such not hamper Presidency influence. Moreover, the analysis reveals three sufficient combinations of conditions for Presidency influence, in which the individual conditions play different roles. The application of QCA to Presidency influence leads to novel insights and stimulates conceptual clarity on the level of and the conditions for influence.