Cytotoxicity profiling of decabromodiphenyl ethane to earthworm (Eisenia fetida): Abnormity-recovery-dysregulation physiological pattern reflects the coping mechanism

Fu, Mengru; Liu, Fang; Abbas, Ghulam; Zhou, Shanqi; Ling, Siyuan; Zhang, Wei; Peng, Cheng; Yang, Jie; Zhou, Bingsheng

doi:10.1016/j.scitotenv.2021.152607

Cited by 13 publications

(4 citation statements)

References 38 publications

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“…All samples were handled following the method in the previous study. 35 The details of sample extraction and purification, GC-MS analysis, and QA/QC are shown in Texts S1−S2, and a typical original chromatogram is also provided in Figure S3. Extraction and Characteristics of MPs.…”

Section: ■ Materials and Methodsmentioning

confidence: 99%

“…The rest of the earthworms were used to measure DBDPE concentration in the tissue directly. All samples were handled following the method in the previous study . The details of sample extraction and purification, GC-MS analysis, and QA/QC are shown in Texts S1–S2, and a typical original chromatogram is also provided in Figure S3.…”

Section: Methodsmentioning

confidence: 99%

“…32,33 Meanwhile, earthworms exposed to 5−100 mg kg −1 DBDPE suffered from tissue damage and apoptosis. 34,35 However, the bioaccumulation interplay and combined toxicity of MPs and DBDPE remain unclear. This study hypothesized that ABS-MPs affect the DBDPE bioaccumulation by earthworms, and both the adsorption of DBDPE on ABS-MPs and the adverse effects of ABS-MPs on the physiological status of earthworms involve the mechanisms.…”

Section: ■ Introductionmentioning

confidence: 99%

“…Earthworm ( Eisinia fetida ) is a model organism for the ecotoxicological risks assessments in the terrestrial system. , Previous studies indicated that MPs, such as polyester, polyethylene terephthalate, polyethylene, and polystyrene, had adverse effects on earthworm egestion rate, growth, and oxidative response, especially MPs with concentrations higher than 0.5% (w/w) and sizes smaller than 0.1 μm. , Meanwhile, earthworms exposed to 5–100 mg kg –1 DBDPE suffered from tissue damage and apoptosis. , However, the bioaccumulation interplay and combined toxicity of MPs and DBDPE remain unclear. This study hypothesized that ABS-MPs affect the DBDPE bioaccumulation by earthworms, and both the adsorption of DBDPE on ABS-MPs and the adverse effects of ABS-MPs on the physiological status of earthworms involve the mechanisms.…”

Section: Introductionmentioning

confidence: 99%

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Insight into Bioaccumulation of Decabromodiphenyl Ethane in Eisenia fetida Increased by Microplastics

Fu,

Tan,

Zhou

et al. 2023

Environ. Sci. Technol.

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The rise of electronics inevitably induced the co-pollution of novel brominated flame retardants (NBFRs) and microplastics (MPs). However, studies on how they interact to influence their bioavailability are scarce. Here, we explored the influence mechanism of acrylonitrile butadiene styrene (ABS)-MPs on the bioaccumulation of decabromodiphenyl ethane (DBDPE) in soil-earthworm microcosms. The influence exhibited a temporal pattern characterized by short-term inhibition and long-term promotion. After 28 days of exposure, DBDPE bioaccumulation in a co-exposure (10 mg kg–1 DBDPE accompanied by 1000 mg kg–1 ABS-MPs) was 2.61 times higher than that in a separate exposure. The adsorption process in the soil, intestines, and mucus introduced DBDPE-carried MPs, which had a higher concentration of DBDPE than the surrounding soil and directly affected the bioavailability of DBDPE. MP-pre-exposure (100, 1000, and 10000 mg kg–1) reduced epidermal soundness, mucus secretion, and worm cast production. This eventually promoted the contact between earthworm and soil particles and enhanced the DBDPE of earthworm tissue by 6%–61% in the next DBDPE-postexposure period, confirming that MPs increased DBDPE bioaccumulation indirectly by impairing the earthworm health. This study indicates that MPs promoted DBDPE bioaccumulation via adsorption and self-toxicity, providing new insight into the combined risk of MPs and NBFRs.

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Section: ■ Materials and Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%