2009
DOI: 10.1590/s0102-695x2009000100009
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Cytotoxicity of Wedelia paludosa D.C. extracts and constituents

Abstract: RESUMO: "Citotoxidade de extratos e constituintes de Wedelia paludosa D.C." Wedelia paludosa D.C. (Asteraceae) é uma planta ornamental facilmente encontrada em várias regiões do Brasil, principalmente nos estados de Santa Catarina, São Paulo, Minas Gerais, Bahia e Pernambuco. Objetivando descobrir novas substâncias citotóxicas a partir desta espécie, o extrato hidrometanólico de W. paludosa (HME) e as frações diclorometânica (FD) e aquosa (FA) resultantes de sua partição em CH 2 Cl 2 -H 2 O foram avaliados uti… Show more

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Cited by 12 publications
(9 citation statements)
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References 29 publications
(27 reference statements)
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“…The BSLB was performed according to the procedure proposed by Batista et al (2009). Brine shrimp eggs were hatched in artificial seawater (40 g/L, sea salt).…”
Section: Brine Shrimp Lethality Bioassaymentioning
confidence: 99%
“…The BSLB was performed according to the procedure proposed by Batista et al (2009). Brine shrimp eggs were hatched in artificial seawater (40 g/L, sea salt).…”
Section: Brine Shrimp Lethality Bioassaymentioning
confidence: 99%
“…This plant is popularly known as "Pseudo-arnica, Margaridão, Pingo- de-ouro, Arnica-do-mato, Picão-da-praia, and Vedélia" and can be found in many regions of Brazil. Despite being considered an ornamental plant owing to the presence of yellow flowers, it has been used in the folk medicine (Batista, Brandão, Braga, & Oliveira, 2009). Some studies have demonstrated different activities for S. trilobata extracts, such as anti-inflammatory, antifungal, trypanosomicidal, antimicrobial, and hypoglycemic (Chiari, et al 1996;Block, Scheidt, Quintão, Santos, & Cechinel-Filho, 1998;Bresciani, et al 2004).…”
Section: Introductionmentioning
confidence: 99%
“…These compounds show wide spectral biological activity, and have been used in traditional medicine, for example, ent-kaurenic acid has been used as anti-microbial, anti-inflammatory (Sosa-Sequera et al, 2010;Cavalcanti et al, 2006), anti-fungal (Boeck et al, 2005), anti-parasitical (Diamantino et al, 2008) and others. While grandiflorenic acid has been reported with diuretic effect (Somova et al, 2001), uterotonic properties (Villa-Ruano et al, 2013) and anti-trypanosomiasis (Batista et al, 2009). Occasionally, cattle consume different species of Espeletia and other paramo vegetation, although of poor quality (Molinillo and Monasterio, 2002).…”
Section: Introductionmentioning
confidence: 99%