Cytotoxicity of DP-Bioglass Paste Used for Treatment of Dentin Hypersensitivity

Kuo, Tien-Chun; Lee, Bor-Shiunn; Kang, Shu-Han; Lin, Fa‐Hsuan; Lin, Chun‐Pin

doi:10.1016/j.joen.2006.12.014

Cited by 35 publications

(30 citation statements)

References 19 publications

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“…The extraction from cell culture medium was performed at a ratio of 1.25 cm 2 /mL (surface of samples/volume of medium). The 3T3 fibroblasts were used for cytotoxicity as previously described (12). Cells were incubated for 24 or 72 hours for cytotoxicity test with the MTT assay.…”

Section: Cytotoxicity Testmentioning

confidence: 99%

A Novel Urethane Acrylate–based Root Canal Sealer with Improved Degree of Conversion, Cytotoxicity, Bond Strengths, Solubility, and Dimensional Stability

Lee

Wang

Fang

et al. 2011

Journal of Endodontics

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Section: Cytotoxicity Testmentioning

confidence: 99%

A Novel Urethane Acrylate–based Root Canal Sealer with Improved Degree of Conversion, Cytotoxicity, Bond Strengths, Solubility, and Dimensional Stability

Lee

Wang

Fang

et al. 2011

Journal of Endodontics

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“…29 These desensitizing agents in conjugation with lasers were claimed to penetrate the tubules for up to 10 mm in previous studies. 30 Sensodyne repair and protect, incorporating Novamin bioactive glass technology, was thus chosen for the study. 31 Earlier studies have prescribed the repeated usage of desensitizing agents to ensure higher clinical effectiveness in dentinal tubule occlusion.…”

Section: Discussionmentioning

confidence: 99%

In vitro Analysis Comparing Efficacy of Lasers and Desensitizing Agents on Dentin Tubule Occlusion: A Scanning Electron Microscope Study

Iyer¹,

Nandakumar²

2014

International Journal of Laser Dentistry

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Dentinal hypersensitivity (DH), one of the commonest causes of dental pain, arises from exposure of dentinal tubules most commonly in the cervical region of the buccal and facial surfaces of the tooth in response to typically thermal, evaporative, tactile, osmotic or chemical stimulus. This study aims at evaluating the efficacy of Er,Cr:YSGG (dual lasers -hard and soft tissue) and diode lasers (soft tissue lasers) against clinically proven dentifrices prescribed by dentists, easily available over the counter, in treating DH. In 60 recently extracted human teeth, cervical cavities were prepared and etched with 17% EDTA to expose the tubules and eliminate smear layer. The teeth were further divided into groups: Er,Cr:YSGG laser, diode laser and commonly used dentifrices chosen on the basis of previous studies. After treatment, the teeth were subjected for scanning electron microscope (SEM) analysis on the same day for quantitative and qualitative analysis of the specimens. Quantitative analysis of the SEM images was done using image analysis software. Er,Cr:YSGG showed superior results in terms of number of tubules per millimeter square, tubule diameter and tubular area. Laser treatment of exposed dentinal tubules with Er,Cr:YSGG promises a noninvasive, pain free and relatively safe treatment option.

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“…The repair or regeneration process in dentin requires living cells reacting to stimuli, some of which may be present as a by-product of the repair procedure from their release from sequestration within dentin, and others by exposure to stimulating or facilitating agents present in applied materials. 104 Bioactive glass, which is an example of the latter, is being studied for tooth desensitization 105,106 and dentin remineralization, alone or as an additive to restorative materials. [107][108][109][110] Bioactive glass-containing materials Several studies have reported on the addition of bioactive glass to dental restoratives.…”

Section: Other Restorativesmentioning

confidence: 99%

Can interaction of materials with the dentin-pulp complex contribute to dentin regeneration?

2010

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Understanding outcomes of the interaction between a dental material and tooth tissue is important in terms not only of biocompatibility but also of the potential for the material to modulate the response of the tissue. This interaction is influenced by many factors, including the chemistry of the material and any of its eluted components or degradation products, and the manner in which the tissue responds to these agents. Past studies of this interaction have primarily been aimed at identifying cytotoxic effects. More recently, investigations have focused on specific cellular responses, and in particular, on understanding how the materials themselves actually may contribute to regenerative processes in the tooth. Recent work has demonstrated the solubilization of proteins from dentin exposed to certain materials, such as calcium hydroxide, mineral trioxide aggregate, and acidic solutions that relate to those used in dentin bonding agents, with the subsequent modulation by these proteins of gene expression in odontoblast-like cells. This work suggests that dentin bridge formation under such materials may be stimulated through this process. Thus, there is much merit in examining both how new dental materials can be developed and how more traditional ones can be modified to preferentially stimulate regenerative processes when preferred. This review summarizes current knowledge about the potential beneficial effects derived from the interaction of dental materials with the dentin-pulp complex, as well as potential future developments in this exciting field.

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Cytotoxicity of DP-Bioglass Paste Used for Treatment of Dentin Hypersensitivity

Cited by 35 publications

References 19 publications

A Novel Urethane Acrylate–based Root Canal Sealer with Improved Degree of Conversion, Cytotoxicity, Bond Strengths, Solubility, and Dimensional Stability

A Novel Urethane Acrylate–based Root Canal Sealer with Improved Degree of Conversion, Cytotoxicity, Bond Strengths, Solubility, and Dimensional Stability

In vitro Analysis Comparing Efficacy of Lasers and Desensitizing Agents on Dentin Tubule Occlusion: A Scanning Electron Microscope Study

Can interaction of materials with the dentin-pulp complex contribute to dentin regeneration?

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