Cytotoxicity, antifungal, antioxidant, antibacterial and photodegradation potential of silver nanoparticles mediated via Medicago sativa extract

Zare-Bidaki, Majid; Aramjoo, Hamed; Mizwari, Zirar M.; Mohammadparast-Tabas, Pouria; Javanshir, Reyhane; Mortazavi‐Derazkola, Sobhan

doi:10.1016/j.arabjc.2022.103842

Cited by 30 publications

(18 citation statements)

References 42 publications

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“…The AgNPs demonstrated effective inhibition of the mycelial growth of these plant pathogenic fungi (Table 2). These findings are in line with previous studies conducted by other researchers, who have also reported the antifungal action of AgNPs against diverse plant pathogenic fungi [49,50]. The results of the current investigation indicate that the biosynthesized AgNPs can effectively curb the proliferation of mycelia in all the examined phytopathogens.…”

Section: Discussionsupporting

confidence: 93%

Bio‐fabrication of silver nanoparticles using an aqueous extract of Quercus baloot: Preparation, characterization and in vitro antimicrobial evaluation

Rabbi,

Nisar,

Nawaz

et al. 2023

Micro & Nano Letters

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In the current study, a novel method was used to synthesize silver nanoparticles (AgNPs) by utilizing Quercus baloot aqueous extract as a reducing agent. The biosynthesized AgNPs were then subjected to various physicochemical characterizations to assess their effectiveness against microbial familiarity. The characterization techniques included ultraviolet‐visible spectro‐photometry (UV‐Vis), scanning electron microscopy (SEM), transmission electron microscopy (TEM), X‐ray diffractometer (XRD), and Fourier‐transform infrared spectroscopy (FTIR). The UV‐Vis analysis revealed a distinctive spectral peak at 420 nm, indicating the presence of silver nanoparticles. SEM imaging displayed the nanoparticle size range of about 100 nm at a magnification of 30,000x, while TEM demonstrated that the nanoparticles had a spherical morphology with a size of approximately 100 nm. Moreover, the crystalline structure of the silver nanoparticles was confirmed by XRD analysis, further validating their successful synthesis. Additionally, FTIR analysis provided evidence of the presence of phytochemicals involved in synthesizing the AgNPs. the biosynthesized silver nanoparticles (AgNPs) were evaluated for antibacterial and antifungal activities. The AgNPs displayed substantial efficacy against common bacterial strains, including Staphylococcus aureus (71%), Escherichia coli (59%), and Klebsiella pneumoniae (64%). Furthermore, they demonstrated significant antifungal activity against plant pathogenic fungi, namely Aspergillus niger (65%), Aspergillus flavus (70%) and Fusarium oxysporum (61%).

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Section: Discussionsupporting

confidence: 93%

Bio‐fabrication of silver nanoparticles using an aqueous extract of Quercus baloot: Preparation, characterization and in vitro antimicrobial evaluation

Rabbi,

Nisar,

Nawaz

et al. 2023

Micro & Nano Letters

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“…It varied from 1 gram [33,34] to 1 kilogram [35] of diferent parts of plants. Most often, 20-25 grams of biomass was used for obtaining an extract [36][37][38]. Te specifc techniques for extraction and analysis also were chosen very diferently.…”

Section: Study Characteristicsmentioning

confidence: 99%

“…Te specifc techniques for extraction and analysis also were chosen very diferently. Grinding [39,40], sieving [41], centrifugation [33], mixing [42], sonication [34], stirring [36,[43][44][45], and dehydration [46] were most often used. Information about these methods and the most important facts are summarized briefy in Table 1.…”

Section: Study Characteristicsmentioning

confidence: 99%

New Insights on Biosynthesis of Nanoparticles Using Plants Emphasizing the Use of Alfalfa (Medicago sativa L.)

Kokina,

Plaksenkova,

Jankovskis

et al. 2024

Journal of Nanotechnology

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Biological synthesis of nanoparticles (NPs) using alfalfa (Medicago sativa L.) and other plants has several advantages such as lower costs, reduction of pollution, and improvement of the environment and human health. Often, biosynthesis is used to synthesize Ag, Au, and ZnO NPs. Less often are also synthesized Cu and Fe NPs. Synthesis with plant extracts from their parts or callus cultures is a widely used method since extracts contain the most significant number of biomolecules. Synthesis with living plants (in vivo) provides NPs with improved properties for better interactions with plants but is used less often due to the long realization time, the need to control the plants’ growing conditions, and difficulty in controlling the size and shape of the synthesized NPs. Here, we performed a systematic review of various methods for the biological synthesis of different metal NPs with different plants, to highlight advantages and disadvantages of mentioned methods. For discussion, results showed that biosynthesis of NPs allows obtaining NPs with reduced toxicity, and their size and shape depend on the type and number of biomolecules present in plants. Plant biomolecules determine the antibacterial and anticancer properties of NPs, as well as increasing the use of NPs in biomedicine, for better drug transport, therefore medicinal plants or sea plants are mostly used for biosynthesis. NPs which were synthesized in marine plants could be a very effective agent against water bacteria; therefore, if NP biosynthesis takes place in water, biological water purification is possible. Limitations of the study included a great methodological diversity of the synthesis, it is still difficult to systematize the synthesis methods, and it seems that each described study uses a different synthesis protocol; therefore, in future studies, it is necessary to clarify which method can provide the most efficient biosynthesis and develop a unified approach.

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“…Plants are commonly used for NP biosynthesis due to the possibility of growing them easily or maintaining them more easily than bacteria and animals. Various agricultural plants, such as alfalfa (Medicago sativa L.) [17][18][19] and Aloe vera L. [20], are used in NP biosynthesis studies because they contain many biomolecules, such as phenols glucose, fructose, ascorbic acid, and citric acid [20][21][22][23], which can divide metal precursors, for example, AgNO 3 and HauCl 4 to Ag and Au NPs [22][23][24].…”

Section: Introductionmentioning

confidence: 99%

“…Biosynthesis with plants can be performed using plant extracts obtained from plant parts, including seeds [25], leaves [19], and fruit [26]. Extracts can also be obtained from plant callus cells.…”

Section: Introductionmentioning

confidence: 99%

In Vivo Biosynthesis of Au and Ag NPs Using Two Medicago sativa L. Genotypes

Kokina,

Plaksenkova,

Jankovskis

et al. 2024

Applied Sciences

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The nano size as well as physical and chemical properties of Au and Ag nanoparticles (NPs) allow them to be used in medicine or plant protection, but chemical solvents used during synthesis makes them toxic and pose a threat to the environment. Chemical NP synthesis can be replaced by in vivo synthesis in which independently growing plants such as alfalfa take up and then split the precursor in their cells down to nano size using synthesis-promoting solvent-biomolecules, which can break down materials without free radicals and have anti-inflammatory, antioxidant effects, making NPs environmentally benign. In this study, two-week-old seedlings of two Medicago sativa L. genotypes, ‘Kometa’ and ‘la Bella’, were exposed to two precursors (AgNO3, HAuCl4) for 24 and 48 h to determine whether in vivo synthesis is possible. Two-beam and certain wavelength spectrophotometry and confocal microscopy confirmed statistically significant (p < 0.05) changes in light absorption and light fluorescence compared to the control. Confocal microscopy showed both precursors visible in the roots of both genotypes. Currently, NP synthesis and visualisation methods require a complex, expensive, and time-consuming sequence of methods. It is important to find an effective, environmentally friendly, and as cheap and simple as possible method for the biosynthesis of NPs.

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Cytotoxicity, antifungal, antioxidant, antibacterial and photodegradation potential of silver nanoparticles mediated via Medicago sativa extract

Cited by 30 publications

References 42 publications

Bio‐fabrication of silver nanoparticles using an aqueous extract of Quercus baloot: Preparation, characterization and in vitro antimicrobial evaluation

Bio‐fabrication of silver nanoparticles using an aqueous extract of Quercus baloot: Preparation, characterization and in vitro antimicrobial evaluation

New Insights on Biosynthesis of Nanoparticles Using Plants Emphasizing the Use of Alfalfa (Medicago sativa L.)

In Vivo Biosynthesis of Au and Ag NPs Using Two Medicago sativa L. Genotypes

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