Cytotoxicity and Characterization of Particles Collected From an Indium–Tin Oxide Production Facility

Badding, Melissa A.; Stefaniak, Aleksandr B.; Fix, Natalie R.; Cummings, Kristin J.; Leonard, Stephen S.

doi:10.1080/15287394.2014.920757

Cited by 33 publications

(57 citation statements)

References 48 publications

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“…In both cell lines the indium compounds exhibited reduced viability after exposure to 50 g/ml or 1 mg/ml for 24 or 48 h with SITO having the greatest impact on cell survival. Significant apoptosis was only induced in RAW 264.7 cells, where SITO was damaging at 50 g/ml and 1 mg/ml, UITO only at 1 mg/ml (Badding et al, 2014).…”

Section: In Vitro Studies On Cellsmentioning

confidence: 97%

“…The mean particle diameters were determined as >200 nm <1 m for In(OH) 3 ), SnO 2 , as >200 nm < 2 m for In 2 O 3 and as 0.5 ± 0.3 m for SITO and SUITO. From these compounds only UITO was capable of producing significant ESR peaks (Badding et al, 2014).…”

Section: Free Radical Studiesmentioning

confidence: 99%

“…The particle diameters and the vehicle used were as described in Badding et al (2014). SITO particles activated nuclear factor kappa B within 3 h of treatment and induced cytokine production (IL-1␤, IL-6, TNF␣, and IL-8) within 24 h in both RAW 264.7 and BEAS-2B cells.…”

Section: In Vitro Studies On Cellsmentioning

confidence: 99%

“…Two independent experiments were performed and at least 50 total cell comets per condition (22-29 comets/replicate) were measured for percent DNA in comet heads versus tails (Badding et al, 2014).…”

Section: In Vitro Experimentsmentioning

confidence: 99%

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The toxicology of indium tin oxide

Bomhard¹

2016

Environmental Toxicology and Pharmacology

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Section: In Vitro Studies On Cellsmentioning

confidence: 97%

Section: Free Radical Studiesmentioning

confidence: 99%

Section: In Vitro Studies On Cellsmentioning

confidence: 99%

Section: In Vitro Experimentsmentioning

confidence: 99%

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The toxicology of indium tin oxide

Bomhard¹

2016

Environmental Toxicology and Pharmacology

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“…Indium tin oxide (ITO) is one of the most popular transparent conductive oxides (TCO) in industry, but expensive and toxic due to its high concentration of indium [1]. Zinc oxide (ZnO) is a suitable candidate for replacing ITO due to its low price, wide band gap of 3.27 eV, good electrical, optical properties and stability in a hydrogen plasma atmosphere [2,3].…”

Section: Introductionmentioning

confidence: 99%

A comparative study on physical properties of Al-doped zinc oxide thin films deposited from zinc acetate and zinc acetylacetonate by spray pyrolysis

Eensalu¹,

Krunks²,

Gromyko³

et al. 2017

energetika

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Herein we present a comparative study on highly transparent, conductive aluminium-doped ZnO (AZO) thin films deposited by pneumatic spray pyrolysis (PSP) of a zinc acetate based solution and a zinc acetylacetonate based solution on soda lime glass. The structural, optical and electrical properties of the films were studied depending on aluminium content in the precursor solution and substrate temperature during deposition (Ts). The solution used to prepare AZO thin films contained 0.2 M zinc acetate or 0.2 M zinc acetylacetonate and aluminium acetylacetonate between 0-15 at.% [Al]/[Zn]. Substrate temperature was varied from 275 to 450 °C. Transmittance and reflectance spectra were recorded by UV-VIS-NIR spectroscopy. Resistivity, mobility and charge carrier density were determined by four point probe measurements in ambient conditions. According to X-ray diffraction analysis, AZO films are highly c-axis oriented until 2-3 at.% [Al]/[Zn] in the spray solution, depending on zinc precursor. Crystallite size is 25-30 nm for AZO films deposited at Ts 400 °C. All AZO films exhibited high average optical transmittance of 76-94% in the visible spectrum 400-800 nm wavelength range. Eg values ranged from 3.32 in undoped ZnO to 3.58 eV in in highly doped AZO films deposited from zinc acetylacetonate due to the formation of secondary AlO x phases. The lowest resistivities were obtained at Ts 400 °C for films deposited from zinc acetate, 3-7.

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Respirable indium exposures, plasma indium, and respiratory health among indium‐tin oxide (ITO) workers

Cummings

Virji

Park

et al. 2016

American J Industrial Med

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Background Workers manufacturing indium-tin oxide (ITO) are at risk of elevated indium concentration in blood and indium lung disease, but relationships between respirable indium exposures and biomarkers of exposure and disease are unknown. Methods For 87 (93%) current ITO workers, we determined correlations between respirable and plasma indium and evaluated associations between exposures and health outcomes. Results Current respirable indium exposure ranged from 0.4 to 108 μg/m3 and cumulative respirable indium exposure from 0.4 to 923 μg-yr/m3. Plasma indium better correlated with cumulative (rs = 0.77) than current exposure (rs = 0.54) overall and with tenure ≥1.9 years. Higher cumulative respirable indium exposures were associated with more dyspnea, lower spirometric parameters, and higher serum biomarkers of lung disease (KL-6 and SP-D), with significant effects starting at 22 μg-yr/m3, reached by 46% of participants. Conclusions Plasma indium concentration reflected cumulative respirable indium exposure, which was associated with clinical, functional, and serum biomarkers of lung disease.

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Cytotoxicity and Characterization of Particles Collected From an Indium–Tin Oxide Production Facility

Cited by 33 publications

References 48 publications

The toxicology of indium tin oxide

The toxicology of indium tin oxide

A comparative study on physical properties of Al-doped zinc oxide thin films deposited from zinc acetate and zinc acetylacetonate by spray pyrolysis

Respirable indium exposures, plasma indium, and respiratory health among indium‐tin oxide (ITO) workers

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