Cytotoxic α-pyrone derivatives from Cryptocarya yunnanensis

Cryptoyunnanones A–H, Complex Flavanones from Cryptocarya yunnanensis

“…Four known α-pyrones were identified as obolactone ( 9 ), , 7′,8′-dihydroobolactone ( 10 ), , cryptobrachytone B ( 11 ), , and cryptobrachytone C ( 12 ) , on the basis of their NMR data.…”

“…Cryptocarya yunnanensis H. W. Li is a species distributed only in the south of Yunnan Province, People’s Republic of China. Our previous study reported the discovery of five new and four known α-pyrones that showed cytotoxicity . As a continuing search for more potential anticancer lead compounds from the genus Cryptocarya , , in this study eight new complex flavanones, cryptoyunnanones A–H ( 1 – 8 ), together with four known α-pyrones, were isolated from the leaves and twigs of C .…”

Two Novel Flavonoids and Cytotoxicity Evaluation from Cryptocarya yunnanensis

“…Cryptocarya yunnanensis H. W. Li, a species endemic to Yunnan province, P. R. China, has been studied previously in our group, which resulted in the discovery of five new α‐pyrones and eight new complex flavanones with cytotoxicity [24,25] . In our continuous research for the genus Cryptocarya , [24–26] a new biflavonoid, cryunchalcone ( 1 ), and a new complex flavanone, cryptoyunnanone I ( 2 ), were obtained from C. yunnanensis . Their structures ( Figure 1) were established due to their spectroscopic data and ECD calculations.…”

Complex Flavanones from Cryptocarya metcalfiana and Structural Revision of Oboflavanone A

“…Cryptocarya metcalfiana Allen, a species distributed only in south mainland China, has never been studied phytochemically. As a continuing search for bioactive constituents from the genus Cryptocarya , − in the current work, nine new flavanone derivatives, cryptometcones A–I ( 1 – 9 ), together with four known analogues, were isolated from the leaves and twigs of C . metcalfiana .…”