2022
DOI: 10.37360/blacpma.22.21.1.07
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Cytotoxic effect of hydroalcoholic extract of Cota tinctoria (L.) J.Gay on AGS and Hep-G2 cancer cell lines

Abstract: Cota tinctoria is a medicinal plant which has been used for management of cancer in folk medicine of various regions. The aim of present study is to investigate cytotoxic activity of different concentrations of hydroalcoholic extract of C. tinctoria flowers on gastric (AGS) and liver (Hep-G2) cancer cell lines as well as Human Natural GUM fibroblast (HUGU) cells. Cell mortality rates were examined after 24, 48 and 72 h incubations using the MTT assay. IC50 of extract on AGS cells after 24, 48 and 72h was 1.46,… Show more

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“…tinctoria were mentioned [ 36 ]. Cytotoxic activity of ethanol extract of C. tinctoria flowers was investigated [ 37 ]. In another study, phenolic constituents, cytotoxic activity, and dyeing properties for the ethanol and aqueous extracts of stem, flower, and root of the plant were studied [ 38 ].…”
Section: Introductionmentioning
confidence: 99%
“…tinctoria were mentioned [ 36 ]. Cytotoxic activity of ethanol extract of C. tinctoria flowers was investigated [ 37 ]. In another study, phenolic constituents, cytotoxic activity, and dyeing properties for the ethanol and aqueous extracts of stem, flower, and root of the plant were studied [ 38 ].…”
Section: Introductionmentioning
confidence: 99%