Cytotoxic effect of achatininH (lectin) from Achatina fulica against a human mammary carcinoma cell line (MCF7)

Indra, Dharmu; Ramamurty, Nalini; Kannan, Ramalingam; Babu, Mary

doi:10.1007/s11626-007-9065-x

Cited by 1 publication

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“…Different parts of the snail have different compositions of their biologically active substances. For example, several studies focused on shell (Chen et al, 2016; Latire et al, 2014), body (Iijima et al, 2003; Li et al, 2014), mucus (Dolashki et al, 2020; Greistorfer et al, 2017; Zhong et al, 2013; Ziomek et al, 2017), and hemolymph (Dharmu et al, 2007; Dolashka et al, 2011; Sperstad et al, 2011). Marine snails (Jo et al, 2017; Khan & Liu, 2019), as well as terrestrial ones (Chinaka et al, 2021; Pitt et al, 2015) are used for extraction of active substances.…”

Section: Introductionmentioning

confidence: 99%

Microbial diversity of garden snail mucus

et al. 2022

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The search for new natural compounds for application in medicine and cosmetics is a trend in biotechnology. One of the sources of such active compounds is the snail mucus. Snail physiology and the biological activity of their fluids (especially the mucus) are still poorly studied. Only a few previous studies explored the relationship between snails and their microbiome. The present study was focused on the biodiversity of the snail mucus used in the creation of cosmetic products, therapeutics, and nutraceuticals. The commonly used cultivation techniques were applied for the determination of the number of major bacterial groups. Fluorescence in situ hybridization for key taxa was performed. The obtained images were subjected to digital image analysis. Sequencing of the 16S rRNA gene was also done. The results showed that the mucus harbors a rich bacterial community (10.78 × 1010 CFU/ml). Among the dominant bacteria, some are known for their ability to metabolize complex polysaccharides or are usually found in soil and plants (Rhizobiaceae, Shewanella, Pedobacter, Acinetobacter, Alcaligenes). The obtained data demonstrated that the snail mucus creates a unique environment for the development of the microbial community that differs from other parts of the animal and which resulted from the combined contribution of the microbiomes derived from the soil, plants, and the snails.

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