“…Biscembranoid diterpenoids were discovered in two species of the genus Lobophytum pauciflorum yielded lobophytones A-S (566-584) [166][167][168], while Sarcophyton producted other analogs, ximaolides A-G (585-591) [169,170], methyl neosartortuate acetate (592) [58], methyl tortuoate A (593), methyl tortuoate B (594) [7], nyalolide (595) [8], bisglaucumlides A-K (596-606) [171,172]. in vitro cytotoxicity against the human nasophyringeal carcinoma CNE-2 cell line, with IC 50 values of 22.7 and 24.7 μg/mL, and the murine P-388 tumor cell line, with IC 50 values of 3.5 and 5.0 μg/mL, respectively [7].…”