Cytotoxic, antioxidant, and cytoprotective properties of polyphenol‐enriched extracts from pecan nutshells in MDA‐MB‐231 breast cancer cells
Lucas E. Ribas,
Fátima B. Gasser,
María E. Baravalle
et al.
Abstract:Phenolic compounds present in plants have demonstrated several biological properties such as antioxidant, antitumor, cardioprotective, and antiproliferative. On the other hand, doxorubicin, a chemotherapeutic widely used to treat breast cancer, usually exhibits chronic cardiotoxicity associated with oxidative stress. Therefore, we aimed to study the effects of phenolic compound‐enriched extract (PCEE) with doxorubicin in breast cancer. To achieve this, after an SPE‐C18‐column purification process of crude extr… Show more
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