Abstract:Reactive Oxygen Species (ROS) are generated during normal cellular metabolic activity, especially in the electron transport chain and in biological redox reactions. Cumene Hydroperoxide, (CHP) a potent source of ROS, is commonly used in the chemical manufacture of phenols, acetone and polymers and can result in inadvertent exposure to individuals working in this chemical industry. CHP is known to initiate lipid peroxidation and increase ROS levels in membranes, which can lead to oxidative stress and cell death… Show more
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