“…Many RBPs show enriched expression in stem and/or progenitor cells, including homologs of the piRNA-binding protein PIWI ( Palakodeti et al, 2008 ; Reddien et al, 2005 ; Rouhana et al, 2014 ), the PUF family protein Pumilio ( Salvetti et al, 2005 ), the DEAD-box helicases Vasa and RCK/p54/Me31B ( Rouhana et al, 2010 ; Shibata et al, 1999 ; Wagner et al, 2012 ; Yoshida-Kashikawa et al, 2007 ), the translational regulators Bruno and MEX-3 ( Guo et al, 2006 ; Solana et al, 2016 ; Zhu et al, 2015 ), the dimethylarginine-associated factors Tudor and PRMT5 ( Rouhana et al, 2012 ; Solana et al, 2009 ), components of the snRNA-processing Integrator complex ( Schmidt et al, 2018 ), LSm splicing factors ( Fernandez-Taboada et al, 2010 ), and the deadenylating complex subunit CCR4-NOT ( Solana et al, 2013 ). Together with RBPs exhibiting constitutive expression, these factors help to orchestrate gene expression, cell fate specification, and differentiation ( Bansal et al, 2017 ; Krishna et al, 2019 ; Lakshmanan et al, 2016 ; Palakodeti et al, 2008 ; Reddien et al, 2005 ; Rouhana et al, 2010 ; Shibata et al, 2016 ; Solana et al, 2016 , 2013 ; Zhu et al, 2015 ).…”