Cytomorphology of Fibroadenoma and Phyllodes Tumour: Diagnostic Perspective - One Year Study at Tertiary Care Centre

Abstract

BACKGROUNDDistinction between Fibroadenoma and Phyllodes tumour is important. Accurate diagnosis of these lesions can be arrived at based upon the triple assessment approach comprising of clinical history and examination; radiological and pathologic examinations. Fine Needle Aspiration Cytology (FNAC) is widely and commonly adopted minimally invasive technique for the pathologic assessment because of its relative accuracy, sensitivity, specificity and ease of use. Distinction between a cellular fibroadenoma and phyllodes tumour poses diagnostic challenge from cytopathologist's perception due to many overlapping features between the two entities. Thorough analysis of cytology smears helps in categorisation of these tumours helping in arriving at a definitive diagnosis. METHODSThe study included 165 patients who presented to our outpatient department, Osmania General Hospital, as breast lump during one year study period between March 2015 and March 2016. FNAC was done for all the cases and their cytomorphological features were studied.A retrospective study of Fine Needle Aspiration Cytology (FNAC) of breast lumps was done and their cytomorphological features were studied and analysed to categorise them into Fibroadenoma and Phyllodes tumour respectively. RESULTSOut of 165 cases presenting with breast lump, the study revealed 55 (33.3%) cases of Fibroadenomas, 10 (6.06%) cases of Phyllodes tumour and the remaining cases were categorised into other breast lesions. CONCLUSIONIn conclusion the present study emphasised the importance of FNAC, which is a minimally invasive OPD technique which helps in distinction of Fibroadenoma and Phyllodes tumour based on their cytomorphological features, thus providing a quick and near accurate diagnosis.