Cytomorphological Study of Palpable Breast Lumps: Spectrum of Lesions and Diagnostic Utility of FNAC

Abstract

Background: Palpable breast lumps are quite common which can be benign or malignant. Carcinoma breast is the second most common cancer after cervical cancer. Fine needle aspiration cytology (FNAC) is a minimally invasive, rapid, reliable and cost-effective outdoor procedure to provide effective diagnosis and way to further planning of treatment without need for biopsy. The objective of the study is to study the spectrum of various breast lesions on cytomorphology and its histopathological correlation. Methods: This was a two years retrospective study from June 2014 to May 2016 including 280 cases aspirated from palpable breast lumps. Physical examination of breast lumps by palpation was done. Cytological diagnosis was made and histopathological correlation was done, wherever available. Results: On cytomorphological study of 280 breast lump aspirates 32 (11.43%) were inflammatory lesions, 180 (64.29%) benign, 6 (2.14%) atypical/probably benign, 8 (2.86%) suspicious of malignancy, 46 (16.43%) malignant and 8 (2.86%) were unsatisfactory for evaluation, of these 280 cases, 70 (25%) were available for histopathological examination. The most common benign lesion in the present study was fibroadenoma 115 (41.07%) and the most common malignant lesion was ductal carcinoma 43 (15.36%). Conclusion: Fine needle aspiration cytology is a rapid and reliable tool to provide effective diagnosis in palpable breast lumps. It should be used as routine diagnostic procedure to provide the effective health care to the patients with breast lesions.

Cytomorphological Spectrum of breast lesions and Diagnostic utility of Fine needle aspiration Cytology

“…Discussion FNAC of breast lesions is a simple, easy and cost effective procedure. The majority of the palpable breast lesions occurred in females in third to fourth decade of life which correlated with the study conducted by Chamdanwale et al 11 and Likhar et al 12 In the present study, breast lesions had more preponderance to right side compared to left which is similar to study conducted by Binayke R et al 13 whereas study by Ahmad F et al 8 showed left preponderance.…”

“…5,6 Breast carcinomas are leading cause of morbidity and mortality in women. 7,8 In Indian, breast carcinoma is the second most common malignancy preceded by cervical carcinoma, comprising 22.2% of all new cancers diagnosis and 17.2% of all cancer deaths. 8 Fine needle aspira tion cytology has become widely accepted as simple, cost effective, diagnostic tool with high sensitivity and specificity.…”

“…7,8 In Indian, breast carcinoma is the second most common malignancy preceded by cervical carcinoma, comprising 22.2% of all new cancers diagnosis and 17.2% of all cancer deaths. 8 Fine needle aspira tion cytology has become widely accepted as simple, cost effective, diagnostic tool with high sensitivity and specificity. 9 The sensitivity and specificity of FNAC as a diagnostic tool for palpable breast lumps are 65-99% and 96-100% respectively.…”

“…9 The sensitivity and specificity of FNAC as a diagnostic tool for palpable breast lumps are 65-99% and 96-100% respectively. 8,10 Therefore, the study aimed to access the cytomorphological spectrum of breast lesions.…”

Study of Breast Lump Cytology Evaluation in Pre-Menopausal Females

“…In present study, among the benign lesions, fibroadenoma was the most common benign lesion 60 (48 %) followed by Proliferative breast lesion without atypia inclusive of fibrocystic disease (30 cases; 24.4%), this study is comparable to study by Faiyaz Ahmad [13] (41.07%) followed by proliferative breast lesion without atypia (14.29%) and Neha Kurmi Patel et al, [14] . who reported 43.5% cases of fibroadenoma and 24.1 % cases of Fibrocystic disease.…”