Cytomorphological comparison of alcohol–formalin cell-block technique with conventional cytology in serous effusions in a low-resource setting
Neelam Kumari,
Manupriya Sharma,
Rashmi Kaul
et al.
Abstract:Our study compared the diagnostic accuracy of the 10% alcohol–formalin cell-block (CB) technique against traditional smears (CS) in serous effusions over 1 year. CB outperformed CS by detecting 7 missed cases and diagnosing 177 benign, 5 suspicious and 26 malignant cases compared to CS's 180 benign, 9 suspicious and 19 malignant cases. Using histopathology as a gold standard, CB showed a sensitivity of 96.4%, specificity of 98.3% and diagnostic accuracy of 98.1%, significantly higher than CS's 79.3% sensitivit… Show more
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