Cytomorphologic features of fine-needle aspiration of liposarcoma

Nemanqani, Dalal; Mourad, Walid A.

doi:10.1002/(sici)1097-0339(199902)20:2<67::aid-dc4>3.0.co;2-d

Cited by 37 publications

(34 citation statements)

References 10 publications

(6 reference statements)

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“…Recent cytologic reports from American investigators did not document specifically the presence or absence of a round cell component among various series (total of 28 cases) of myxoid liposarcomas. 8,18,19 Whether this represents a failure to identify a round cell component or an exclusion of such tumors from these studies is unclear. Nemanqani and Mourad 19 mention the presence of areas of "in- creased cellularity" in myxoid liposarcoma but these appear to represent foci of obvious multivacuolated lipoblasts and not round cell differentiation.…”

Section: Discussionmentioning

confidence: 99%

“…8,18,19 Whether this represents a failure to identify a round cell component or an exclusion of such tumors from these studies is unclear. Nemanqani and Mourad 19 mention the presence of areas of "in- creased cellularity" in myxoid liposarcoma but these appear to represent foci of obvious multivacuolated lipoblasts and not round cell differentiation. When the full spectrum of myxoid and round cell liposarcomas are analyzed, pure myxoid (absence of a round cell component) liposarcoma represents between 28 -57% of the cases, suggesting that round cell differentiation may be more common than initially believed.…”

Section: Discussionmentioning

confidence: 99%

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The value of fine-needle aspiration biopsy in the differential diagnosis of adult myxoid sarcoma

Kilpatrick

Ward

Bos

2000

Cancer

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

The value of fine-needle aspiration biopsy in the differential diagnosis of adult myxoid sarcoma

Kilpatrick

Ward

Bos

2000

Cancer

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“…[14] In their study on MLPS, Nemanqani et al . [27] reported plexiform pattern in 8 out of 10 cases and Kilpatrick et al . [13] noted this pattern in 3 out of 4 cases having hypercellular round cells.…”

Section: Discussionmentioning

confidence: 99%

Hypercellular round cell liposarcoma: A comprehensive cytomorphologic study and review of 8 cases

Chufal

Pant

et al. 2017

J Cytol

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Background:Myxoid and round cell liposarcomas (RCL) are low and high-grade counterparts of a common subtype of liposarcomas (LPS), representing a histologic continuum.Aims:The aim was to study the cytomorphology of hypercellular RCL and to look for features that differentiate RCL from other sarcomas displaying round cells with myxoid change.Materials and Methods:Eight cases of hypercellular RCL were identified retrospectively in which round cell component constituted greater than 75% of the area. Cytomorphological features were studied in detail.Results:Four cases were predominantly composed of round cells, out of which 2 were entirely composed of round cells. Myxoid metachromatic stroma was absent in 2 cases, while it was present in ample amounts in the remaining 6 cases. Spindle cells were completely absent in 5 cases and lipoblasts were observed in a single case of RCL. Plexiform vascular capillaries were seen in 4 cases. Adherence of neoplastic round cells around thin capillaries (ANAC) was observed in 7 cases.Conclusions:Plexiform capillary plexus and ANAC should be separately evaluated. The latter feature is the most consistent one, and is an important clue to the adipocytic nature of the neoplasm when hypercellular round cell areas are aspirated. Confident diagnosis of hypercellular RCL can be made on the basis of this feature. Lipoblasts, although specific, are seen in few cases. The rest of the features are nonspecific and useful only in combination.

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“…1,5,6,[8][9][10][11][12][13] FNA is a useful screening tool for soft tissue masses. Ancillary techniques like immunohistochemistry and cytogenetics are often indispensable for definitive classification.…”

Section: Soft Tissuementioning

confidence: 99%

“…4,11,24,43,44 Hibernoma The hibernoma is a rare benign tumor of brown fat that occurs predominantly in adults aged 20 to 50 years. Atrophic muscle fibers in some lipoma aspirates can mimic the floret cells of a pleomorphic lipoma, but atypical mononucleated stromal cells are absent.…”

Section: Cytomorphology Of Lipomamentioning

confidence: 99%

Soft Tissue

Qian¹

2009

Cytology

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Cytomorphologic features of fine-needle aspiration of liposarcoma

Cited by 37 publications

References 10 publications

The value of fine-needle aspiration biopsy in the differential diagnosis of adult myxoid sarcoma

The value of fine-needle aspiration biopsy in the differential diagnosis of adult myxoid sarcoma

Hypercellular round cell liposarcoma: A comprehensive cytomorphologic study and review of 8 cases

Soft Tissue

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