Cytomegalovirus infections in infants in Uganda: Newborn-mother pairs, neonates with sepsis, and infants with hydrocephalus

Paenibacillus spp infection among infants with postinfectious hydrocephalus in Uganda: an observational case-control study

“…Patients with postinfectious hydrocephalus also had lower haemoglobin concentration (10·6 g/dL [1·6]) than the non-postinfectious hydrocephalus group (13·6 g/dL [2·9]; p<0·0001]. 13 The two groups were not different with regard to sex, HIV exposure, and detection of cytomegalovirus in the blood ( appendix pp 7–8). CT scoring was based on the presence of loculation, calcification, debris within fluid collections, or abscess formation, and postinfectious hydrocephalus was associated with more severe brain CT scores, with 122 (62%) of 196 patients having scores of 2 or more compared with ten (6%) of 178 patients in the non-postinfectious hydrocephalus group (odds ratio 29·2, 95% CI 14·6–58·5; p<0·0001).…”

“…For the mother–newborn pair study, we recruited labouring expectant mothers from the Mbarara Regional Referral Hospital (Mbarara, Uganda) and Mbale Regional Referral Hospital (Mbale, Uganda) between May 20, 2016 and May 8, 2017, as previously described. 13 , 14 We recruited women (aged ≥18 years) who were in labour and able to provide informed written consent in a local language. We included women who delivered at term (>37 weeks estimated gestational age).…”