2008
DOI: 10.1002/dc.20814
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Cytology of metastatic prostate cancer following orchiectomy and antiandrogen therapy: A diagnostic challenge

Abstract: Androgen deprivation therapy induces apoptosis and decreases both cell proliferation and angiogenesis in prostate adenocarcinoma. The molecular alterations following androgen ablation translate into unique cytologic features in both primary and metastatic prostate adenocarcinoma. We describe the cytologic appearance of metastatic prostate carcinoma following both surgical castration and androgen deprivation therapy.

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Cited by 1 publication
(1 citation statement)
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“…PSA and PSAP are two widely used markers in suggesting and/or confirming prostatic origin. 12,13,21,22 Cells of adrenal cortical origin commonly express inhibin, melan A, and calretinin. 20,23 Adrenal medullary tumors should express synaptophysin and chromogranin, and conventional renal cell carcinomas often stain with RCC.…”
Section: Discussionmentioning
confidence: 99%
“…PSA and PSAP are two widely used markers in suggesting and/or confirming prostatic origin. 12,13,21,22 Cells of adrenal cortical origin commonly express inhibin, melan A, and calretinin. 20,23 Adrenal medullary tumors should express synaptophysin and chromogranin, and conventional renal cell carcinomas often stain with RCC.…”
Section: Discussionmentioning
confidence: 99%