Cytology of breast-lesions

Makhija, Shreya; Patil, Suwarna

doi:10.18231/j.achr.2020.016

Cited by 2 publications

(1 citation statement)

References 8 publications

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“…The triple test approach (physical examination, radiology, and cytopathology) is used in the evaluation of breast lesions. Fine needle aspiration cytology (FNAC), one of the “triple test” approaches for evaluating breast lumps distinguish neoplastic and non-neoplastic lesions of the breasts [ 7 , 8 ]. This technique is rapid, reliable, highly acceptable by patients, cost-effective, and has low complication rates [ 9 , 10 ].…”

Section: Introductionmentioning

confidence: 99%

Cytomorphological patterns of breast lesions among women with palpable breast lumps attending select teaching and referral hospitals in Kenya: a descriptive cross-sectional study

Rioki¹,

Muchiri²,

Mweu³

et al. 2023

Pan Afr Med J

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Introduction breast lumps account for a greater number of lesions in women attending surgical clinics in the developing world. Breast cancer which mostly presents as a breast lump is the leading cancer in Kenya, with an incidence of 12.5%. The study aims to describe the patterns of breast lesions in women presenting with palpable breast lumps in two major referral hospitals in Kenya. Methods seven hundred and sixty-eight study participants with palpable lumps underwent fine needle aspiration cytology (FNAC). Sociodemographic data were captured using structured questionnaires. The FNAC materials were evaluated using the International Academy of Cytology Yokohama System (IACYS) and the lesions were classified into five-tier categories. Frequencies and percentages were used to summarize qualitative variables. Results of 768 smears, 84.8% (n=651) were adequate for evaluation while 15.2% (n=117) were inadequate. Neoplastic lesions comprised 84.5% (n=550) and non-neoplastic 15.5% (n=101). Benign lesions accounted for 83.6% of the lesions followed by breast carcinoma (10.4%). Ductal carcinoma comprised 98.5% of cancerous lesions. The age group most affected with ductal carcinoma and suspicious lesions was 20-34 years (37.3% and 55.6% respectively). Fibroadenoma formed the bulk of the benign lesions identified (44.1%). Suspicious of malignancy was 4.1% (n=27). The age group with the most lesions (47.5%) was 20-34 years. Conclusion a wide spectrum of breast lesions was established. Such include inflammatory, atypical, benign, suspicious of malignancy, and malignant lesions. Fibroadenoma was a common lesion diagnosed. The age group most affected by malignant lesions was 16-49 years, necessitating enhanced screening of women with breast lumps in our setups.

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Section: Introductionmentioning

confidence: 99%

Cytomorphological patterns of breast lesions among women with palpable breast lumps attending select teaching and referral hospitals in Kenya: a descriptive cross-sectional study

Rioki¹,

Muchiri²,

Mweu³

et al. 2023

Pan Afr Med J

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A comparative study of breast lesions using the IAC Yokohama System for reporting breast cytopathology against histopathological biopsy

Joshi,

Varma,

Pande

2024

MGM J Med Sci

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Background: Breast lumps pose a significant health concern globally, contributing to both illness and death. The International Academy of Cytology (IAC) Yokohama system has established a uniform method for reporting breast cytology, categorizing it into five groups: inadequate, benign, atypical, suspicious, and malignant. Aims and Objectives: This study primarily aimed to evaluate breast lesions using the IAC Yokohama System and compare the results with those of corresponding histopathological biopsies. Additionally, the study aimed to analyze the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy of breast fine-needle aspiration cytology (FNAC) and determine the risk of malignancy associated with each category. Materials and Methods: In this study, 92 cases were analyzed and categorized according to the IAC Yokohama System. Sensitivity, specificity, PPV, NPV, diagnostic accuracy, and risk of malignancy were determined based on histopathological diagnosis, which was considered the reference standard. Results: Among the 92 breast FNACs, the risk of malignancy for the categories insufficient, benign, atypical, suspicious, and malignant were 0%, 0%, 18.75%, 100%, and 100%, respectively. The highest sensitivity (100%) was achieved when considering atypical, suspicious, and malignant cases as positive results. The specificity was highest (100%) when only malignant or both malignant and suspicious cases were considered positive results. The highest diagnostic accuracy (95.65%) was observed when including malignant and suspicious cases as positive results. Conclusion: Implementing the IAC Yokohama System for reporting breast cytopathology through structured reporting will enhance the quality, clarity, and reproducibility of reports among pathologists and clinicians, which would result in enhanced patient care and management.

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Cytology of breast-lesions

Cited by 2 publications

References 8 publications

Cytomorphological patterns of breast lesions among women with palpable breast lumps attending select teaching and referral hospitals in Kenya: a descriptive cross-sectional study

Cytomorphological patterns of breast lesions among women with palpable breast lumps attending select teaching and referral hospitals in Kenya: a descriptive cross-sectional study

A comparative study of breast lesions using the IAC Yokohama System for reporting breast cytopathology against histopathological biopsy

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